Evidence map›Paper›PMID 40786269›Full record

ArticleCureus2025

"I Can't Lift My Legs": An Interesting Presentation Leading to the Diagnosis of Anti-synthetase Syndrome.

Javed A Hussain, Chinju Antony, Madan Thirunavukarasu, Athar Yasin

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Javed A HussainEmergency Medicine, Peterborough City Hospital, Peterborough, GBR.
Chinju AntonyEmergency Medicine, Peterborough City Hospital, Peterborough, GBR.
Madan ThirunavukarasuEmergency Medicine, Peterborough City Hospital, Peterborough, GBR.
Athar YasinEmergency Medicine, Peterborough City Hospital, Peterborough, GBR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anti-synthetase syndrome (ASS) is an autoimmune disorder that often manifests through lung involvement such as interstitial lung disease, inflammation of the muscles, and symptoms affecting the joints, including pain or arthritis. Identifying ASS involves a multidisciplinary effort between rheumatologists and lung specialists, using a combination of blood work, imaging techniques, and, in some cases, biopsies of muscle or lung tissue to reach a diagnosis. Treatment usually involves corticosteroids along with other immunosuppressive medications. In this case, we explore the diagnostic journey of a 37-year-old patient who initially presented with an unusual complaint: difficulty lifting his leg, alongside a range of other symptoms. This case highlights the complexity and challenges involved in identifying anti-synthetase syndrome.

Indexed as

anti-jo 1 antibodiesantisynthetase syndrome (ass)creatinine kinasecyclophosphamide treatmentild interstitial lung disease

Identifiers

PMID40786269
PMCPMC12334074

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.