Evidence map›Paper›PMID 40786169›Full record

ReviewFrontiers in public health2025

Unraveling the complex relationship between night shift work and diabetes: exploring mechanisms and potential interventions.

Yuye Zhu, Jing Mi

Abstract readReview
In one paragraph

Review in Frontiers in public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Obesity and metabolic disease in migrants: a role for the gut microbiome?Frontiers in clinical diabetes and healthcare · 2025
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Yuye ZhuXianyang Vocational Technical College, Xianyang, Shaanxi, China.
Jing MiXianyang Vocational Technical College, Xianyang, Shaanxi, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It is a topic of increasing concern that the prevalence of night shift work in our 24/7 society is linked to diabetes mellitus. The purpose of this paper is to thoroughly examine existing research on the intricate connection between diabetes and night shift work, with a specific focus on underlying factors including insufficient sleep, disruptions in circadian rhythms, and changes in melatonin levels. Research has shown that the act of working overnight is linked to an increased likelihood of developing type 2 diabetes mellitus (T2DM), despite the fact that the exact reasons for this connection remain unclear. Insufficient sleep and disruption of the natural sleep-wake cycle, which are common consequences of working night shifts, can result in a reduced response to insulin and dysfunctional processing of glucose in the body. Moreover, changes in the production of melatonin, a hormone closely associated with the body's natural sleep-wake cycle, may have a significant impact. Although working the night shift presents numerous difficulties, interventions targeting the enhancement of sleep quality, adjustment of circadian rhythms, and increase in melatonin levels show potential in reducing the risk of developing T2DM. Further studies must persist in exploring these mechanisms and implementing successful tactics to safeguard the wellbeing of shift workers in our current societal context.

Indexed as

Diabetes Mellitus, Type 2Shift Work ScheduleWork Schedule ToleranceCircadian RhythmHumansMelatoninSleep DeprivationMelatonincircadian rhythmsmelatoninnight shift worksleep deprivationtype 2 diabetes mellitus

Identifiers

PMID40786169
PMCPMC12331512

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.