ArticleQuantitative imaging in medicine and surgery2025
Effect of simultaneous multislice acceleration on the quantitative measurements of diffusion-weighted imaging, intravoxel incoherent motion, and diffusion kurtosis imaging in hepatocellular carcinoma and abdominal organs.
Article in Quantitative imaging in medicine and surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- Performance of simultaneous multislice diffusion-weighted imaging using monoexponential, intravoxel incoherent motion, and diffusion kurtosis models: assessment of microvascular invasion and histologic grade in hepatocellular carcinoma.Cancer imaging : the official publication of the International Cancer Imaging Society · 2025Article
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7 authors.
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Abstract
Background: Although simultaneous multislice (SMS) acceleration shortens abdominal diffusion-weighted imaging (DWI) scans, its effect on quantitative hepatocellular carcinoma (HCC) measurements is unclear. This study aimed to evaluate SMS acceleration effects on DWI-derived quantitative measurements in HCC and the upper abdominal solid organs. Methods: This prospective cross-sectional study initially enrolled 205 patients with clinically suspected HCC. Free-breathing conventional (CON) and SMS-accelerated monoexponential DWI, diffusion kurtosis imaging (DKI), and intravoxel incoherent motion (IVIM) were performed. Two radiologists independently measured the apparent diffusion coefficient (ADC) for monoexponential DWI, mean kurtosis, and mean diffusivity for DKI, as well as the pure diffusion coefficient and perfusion fraction ( Results: A total of 113 patients comprising 129 HCCs were included in the study. The ADC values from SMS-DWI were significantly lower than those from CON-DWI in HCC (P=0.003). Moreover, the Conclusions: Compared with CON sequences, SMS acceleration did not affect most quantitative parameters in HCC or the upper abdominal organs. However, the monoexponential DWI-derived ADC value and IVIM-derived
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