Evidence map›Paper›PMID 40785809›Full record

ArticleAnnals of surgical treatment and research2025

Differentiating oncocytic carcinoma from oncocytic adenoma: a comprehensive evaluation of preoperative characteristics and diagnostic approaches in a retrospective cohort study.

Eunji Kim, Jun Hyun Park, Ji-Young Park, Sang-Woo Lee, Jin Hyang Jung

Abstract read
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In one paragraph

Article in Annals of surgical treatment and research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Eunji KimDivision of Thyroid and Endocrine Surgery, Department of Surgery, Kyungpook National University Chilgok Hospital, Daegu, Korea.ORCID https://orcid.org/0009-0009-0484-0588
Jun Hyun ParkDivision of Thyroid and Endocrine Surgery, Department of Surgery, Kyungpook National University Chilgok Hospital, Daegu, Korea.ORCID https://orcid.org/0000-0002-7800-6555
Ji-Young ParkDepartment of Pathology, Kyungpook National University Chilgok Hospital, School of Medicine, Kyungpook National University, Daegu, Korea.ORCID https://orcid.org/0000-0002-7571-1064
Sang-Woo LeeDepartment of Nuclear Medicine, Kyungpook National University Chilgok Hospital, School of Medicine, Kyungpook National University, Daegu, Korea.ORCID https://orcid.org/0000-0002-7196-5366
Jin Hyang JungDivision of Thyroid and Endocrine Surgery, Department of Surgery, Kyungpook National University Chilgok Hospital, Daegu, Korea.ORCID https://orcid.org/0000-0003-2607-1686

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Oncocytic carcinoma (OCA) has been reclassified from follicular thyroid carcinoma due to its unique features. Its rarity has resulted in limited studies on differentiating OCA from oncocytic adenoma (OA). This study aimed to compare the clinicopathologic and preoperative features of OCA and OA and evaluate the effectiveness of ultrasonography and cytology. Methods: We conducted a retrospective study involving 83 patients (23 with OCA and 60 with OA) who underwent thyroid surgery between 2011 and 2024. We reviewed clinical, ultrasonographic, cytologic, and histopathologic data to assess diagnostic performance. Results: OCA cases had larger tumors than OA in both sonographic (4.2 ± 1.7 cm Conclusion: Predicting malignancy in oncocytic neoplasms is challenging. Larger tumor size, higher ACR TI-RADS scores, and trabecular formation are potential indicators for OCA. Cytologic subcategorization within Bethesda IV suggests follicular neoplasms carry a higher malignancy risk than oncocytic neoplasms. Multicenter studies are needed to validate these findings.

Indexed as

CytologyHurthle cellThyroid cancerThyroid neoplasmsUltrasonography

Identifiers

PMID40785809
PMCPMC12329133

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