Evidence map›Paper›PMID 40785796›Full record

ArticleTobacco induced diseases2025

Association between maternal smoking during pregnancy and attention-deficit/hyperactivity disorder (ADHD) in children aged 4-15 years: A secondary data analysis from the NHANES dataset.

Baomei He, Junxiong Peng, Mengqi Wu, Yanbing Deng, Ying Zhang

Abstract read
In one paragraph

Article in Tobacco induced diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Baomei HeCenter for Reproductive Medicine, Department of Pediatrics, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, China.
Junxiong PengDepartment of Pediatrics, Xianju People's Hospital, Zhejiang Southeast Campus of Zhejiang Provincial People's Hospital, Affiliated Xianju's Hospital, Hangzhou Medical College, Xianju, China.
Mengqi WuCenter for Reproductive Medicine, Department of Pediatrics, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, China.
Yanbing DengCenter for Reproductive Medicine, Department of Pediatrics, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, China.
Ying ZhangCenter for Reproductive Medicine, Department of Pediatrics, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe association between maternal smoking during pregnancy (MSDP) and the risk of attention-deficit hyperactivity disorder (ADHD) in children remains inconclusive. This study aims to investigate the relationship between MSDP and ADHD in children aged 4-15 years, with a particular focus on sex differences.

methodsThis secondary analysis used cross-sectional data from the 1999-2002 National Health and Nutrition Examination Survey (NHANES), comprising 5548 US children and adolescents aged 4-15 years. Inclusion criteria comprised complete maternal smoking history during pregnancy and parent-reported ADHD diagnosis data. Multivariable logistic regression models were employed to assess the association between MSDP and ADHD, with further stratified analyses.

resultsMultivariable logistic regression analysis identified a significant association between MSDP exposure and elevated odds of ADHD (OR=2.11; 95% CI: 1.48-3.00). Sex-stratified analyses revealed that this association was more pronounced in female children (OR=4.18; 95% CI: 2.17-8.03) than in male children (OR=1.64; 95% CI: 1.13-2.38), the interaction between groups was significant (p for interaction <0.01).

conclusionsMSDP showed a statistically significant association with higher ADHD odds, with more pronounced estimates observed in females compared to males.

Indexed as

attention-deficit/hyperactivity disorder (ADHD)childrenmaternal smoking during pregnancyNational Health and Nutrition Examination Surveysex differences

Identifiers

PMID40785796
PMCPMC12332854

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.