ArticleIranian journal of microbiology2025
A comparative study on diagnostic accuracy of rapid card test, IgM ELISA and real time-PCR in detecting scrub typhus infection: a cross-sectional study from tertiary care hospital.
Article in Iranian journal of microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background and Objectives: Scrub typhus, caused by Materials and Methods: This cross-sectional study was conducted on 192 patients with suspected Scrub typhus at a tertiary care hospital from June to November 2024. Diagnostic tests included Rapid Card, IgM ELISA, and RT-PCR. Sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and accuracy were calculated, along with clinical and demographic data. Results: IgM ELISA had the highest sensitivity (96.30%) and specificity (100%), followed by Rapid Card (sensitivity: 93.55%, specificity: 99.38%) and RT-PCR (sensitivity: 92.86%, specificity: 99.44%). Common symptoms included fever (99.4%) and headache (95.8%). Positive cases were mostly males (56.7%-64.3%) and individuals aged 21-40 years. Conclusion: IgM ELISA shows high sensitivity and specificity for Scrub typhus, while RT-PCR aids early detection. The Rapid Card offers a quick field alternative. Combining molecular and serological methods can enhance diagnostic accuracy.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.