Evidence map›Paper›PMID 40785662›Full record

ReviewAnimal models and experimental medicine2025

Research progress on traditional Chinese medicine animal models of post-stroke depression and pathological insights.

Jielin Wang, Wenlu Ma, Wei Wu, Yujuan Fu, Hui Li

Abstract readReview
In one paragraph

Review in Animal models and experimental medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jielin WangSchool of Basic Medical Science, Changchun University of Chinese Medicine, Changchun, P.R. China.
Wenlu MaSchool of Basic Medical Science, Changchun University of Chinese Medicine, Changchun, P.R. China.
Wei WuJilin Ginseng Academy, Changchun University of Chinese Medicine, Changchun, P.R. China.
Yujuan FuSchool of Basic Medical Science, Changchun University of Chinese Medicine, Changchun, P.R. China.
Hui LiJilin Ginseng Academy, Changchun University of Chinese Medicine, Changchun, P.R. China.ORCID 0000-0002-3039-2813

Funding

Jilin Provincial Department of Education JJKH20230958KJJilin Scientific and Technological Development Program YDZJ202401092ZYTS
6 · The paper itself

Abstract

Post-stroke depression (PSD) is a common psychiatric complication affecting nearly one-third of stroke survivors, leading to increased disability, mortality, and cognitive decline. Traditional Chinese Medicine (TCM) has proven effective in treating PSD through syndrome differentiation, yet existing animal models primarily reflect Western medical concepts and fail to incorporate the TCM principle of "" (treating the same disease with different methods). This paper provides a review of the current methods for constructing animal models of post-stroke depression (PSD) from the perspective of Traditional Chinese Medicine (TCM) syndrome differentiation and proposes multi-dimensional assessment indicators. By integrating TCM theories with modern biomedical techniques, this study offers a comprehensive framework for deepening the understanding of the pathogenesis and therapeutic evaluation of PSD. This approach not only contributes to advancing PSD research but also paves the way for innovative treatment strategies that combine traditional and modern medicine.

Indexed as

DepressionDisease Models, AnimalMedicine, Chinese TraditionalStrokeAnimalsHumansanimal modelsintegrative medicinepost‐stroke depressiontraditional Chinese medicine

Identifiers

PMID40785662
PMCPMC12464874

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.