ArticleHead & neck2026
Oncological Impact of Surgical Margin Status After Transoral Laser Microsurgery for Early Glottic Cancer.
Article in Head & neck, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Comparison of oncological outcomes between transoral laser microsurgery and open partial laryngectomy in T2 glottic carcinoma with anterior commissure involvement.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026Article
- Oncological Impact of Surgical Margin Status After Transoral Laser Microsurgery for Early Glottic Cancer.Head & neck · 2026Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTransoral laser microsurgery is a well-established treatment for early glottic cancer. However, managing patients with close/positive margins remains debated. This study analyzes the relationship between resection margins and oncologic outcomes.
methodsPatients with early glottic cancer who underwent transoral laser microsurgery were included. We compared clinical characteristics, recurrence-free survival, laryngeal preservation, and disease-specific survival between negative and close/positive margin groups.
resultsAmong 107 patients, 49 (45.8%) had close/positive margins. The recurrence-free survival rate was significantly lower in the close/positive margin group. Anterior commissure involvement was a significant risk factor for recurrence. The median recurrence time for the close/positive margin group was 18.5 months, similar to the negative margin group. Laryngeal preservation and disease-specific survival were similar between groups with > 95%.
conclusionsPatients with close/positive margins in early glottic cancer showed similar disease-specific survival and laryngeal preservation rates as negative margins; despite lower recurrence-free survival, suggesting a follow-up approach is sufficient.
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