Evidence map›Paper›PMID 40785514›Full record

ArticleJournal of global health2025

An investigation into the impact of family integrated care on extrauterine growth restriction at discharge in very low birth weight infants: a multi-centre study.

Meng-Fan Qiu, Yi Zhang, Ying-Zi Tang, Ya-Lan Dou, Yuan Wang, Tian-Chan Lyu, Qiao-Ling Fan, Yue-Lan Ma, Fang Li, Hui Rong and 17 more

Registry-linked trialAbstract readMulticenter Study
In one paragraph

Article in Journal of global health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06550440 (The Impact of Family Integrated Care on the Occurrence of Extrauterine Growth Restriction at Discharge in Very Low Birth Weight Infants), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06550440 completednot on this map

The Impact of Family Integrated Care on the Occurrence of Extrauterine Growth Restriction at Discharge in Very Low Birth Weight Infants: a Multicenter, Retrospective Case-control Study

TypeobservationalSponsorChildren's Hospital of Fudan UniversityRan2021 to 2024Enrolled1,255ConditionsVery Low Birth Weight InfantArmsfamily integrated care
3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Alberta family integrated careFrontiers in pediatrics · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

27 authors.

Meng-Fan Qiu *Fujian Key Laboratory of Neonatal Diseases, Xiamen Key Laboratory of Neonatal Diseases, Xiamen Children's Hospital (Children's Hospital of Fudan University at Xiamen), Xiamen, China.
Yi Zhang *Department of Neonatology, The Affiliated Maternity and Child Health Care Hospital of Nantong University, Nantong, China.
Ying-Zi Tang *Department of Neonatology, Maternal and Child Health Hospital of Guangxi Zhuang Autonomous Region, Nanning, China.
Ya-Lan DouDepartment of Clinical Epidemiology and Clinical Trial Unit, Children's Hospital of Fudan University, Shanghai, China.
Yuan WangNeonatal Intensive Care Unit, Children's Hospital of Fudan University, Shanghai, China.
Tian-Chan LyuNeonatal Intensive Care Unit, Children's Hospital of Fudan University, Shanghai, China.
Qiao-Ling FanNeonatal Intensive Care Unit, Children's Hospital of Shanghai, Shanghai, China.
Yue-Lan MaNeonatal Intensive Care Unit, Suzhou Municipal Hospital, Suzhou, China.
Fang LiPediatric Internal Medicine, Children's Hospital of Nanjing Medical University, Nanjing, China.
Hui RongPediatric Internal Medicine, Children's Hospital of Nanjing Medical University, Nanjing, China.
Yun-Fei TangPediatric Department, Wuxi Children's Hospital, Wuxi, China.
Wei-Wei GuNeonatal Intensive Care Unit, Ningbo Women and Children's Hospital, Ningbo, China.
Xiao-Chun ChenNeonatal Intensive Care Unit, Yuying Children's Hospital of Wenzhou Medical university, Wenzhou, China.
Dan LiuDepartment of Neonatology, Zhejiang Maternal Hospital, Hangzhou, China.
Hua WangDepartment of Neonatology, Zhejiang Maternal Hospital, Hangzhou, China.
Juan XiaoDepartment of Neonatology, The First Affiliated Hospital of Anhui Medical University, Hefei, China.
Li-Li ZhangDepartment of Neonatology, The First Affiliated Hospital of Anhui Medical University, Hefei, China.
Yan WangDepartment of Neonatology, Anhui Provincial Children's Hospital, Hefei, China.
Ru-Ming YeFujian Key Laboratory of Neonatal Diseases, Xiamen Key Laboratory of Neonatal Diseases, Xiamen Children's Hospital (Children's Hospital of Fudan University at Xiamen), Xiamen, China.
Dan LiFujian Key Laboratory of Neonatal Diseases, Xiamen Key Laboratory of Neonatal Diseases, Xiamen Children's Hospital (Children's Hospital of Fudan University at Xiamen), Xiamen, China.
Xiao-Xia LiDepartment of Neonatology, People's hospital of Longhua, Shenzhen, China.
Yu PangDepartment of Neonatology, Yulin Maternal and Child Health Care Hospital, Yulin, China.
Mei LinDepartment of Neonatology, Affiliated Hospital of Youjiang Medical College for Nationalities, Baise, China.
Mei LinDepartment of Neonatology, Qinzhou Maternal and Child Health Hospital, Qinzhou, Guangxi, China.
Yan XuanDepartment of Nursing, Hainan Women and Children's Medical Centre, Haikou, China.
Xiao-Jing HuDepartment of Nursing, Children's Hospital of Fudan University, Shanghai, China.
Research Group of Developmental Care for Very Low Birth Weight Infants in China

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Family integrated care (FIC) encourages parental involvement in neonatal intensive care units (NICU) and has been found to promote weight gain in preterm infants. Extrauterine growth restriction (EUGR) results from inadequate growth among very low birth weight infants (VLBWI), which has been found to contribute to parental anxiety. To address an existing gap in research, we aimed to examine the impact of parental involvement on EUGR at discharge in VLBWI. Methods: We conducted a retrospective, multi-centre case-control study involving VLBWIs admitted to 17 NICUs across eight southeastern Chinese provinces and cities from February 2021 to November 2023. We categorised cases and control groups based on the presence of EUGR at discharge and compared their perinatal and hospitalisation characteristics, as well as FIC duration, using a generalised linear mixed model. Results: EUGR in VLBWI at discharge was associated with birth weight (odds ratio (OR) = 0.547; 95% confidence interval (CI) = 0.490, 0.610), gestational week (<28 weeks) (OR = 3.101; 95% CI = 1.909, 5.038), Apgar score at 1 minute ≤7 (OR = 1.525; 95% CI = 1.119, 2.079), being small for gestational age (OR = 3.269; 95% CI = 1.547, 6.908), maternal gestational hypertension (OR = 1.868; 95% CI = 1.270, 2.748), necrotising enterocolitis (OR = 2.254; 95% CI = 1.386, 3.667), and total FIC duration. Based on literature and clinical practice, we divided the total FIC duration into three groups. We found that the lowest OR was associated with >18 hours of care, followed by ≤18 hours, while the highest was associated with 0 hours of care. Conclusions: We identified higher birth weight and FIC as protective factors against EUGR at discharge in VLBWI. In contrast, we recognised gestational age <28 weeks, an Apgar score ≤7 at 1 minute, small for gestational age, maternal gestational hypertension, and necrotising enterocolitis as risk factors. Nevertheless, further research is required to analyse the relationship between FIC and EUGR at discharge. Registration: ClinicalTrials.gov (NCT06550440).

Indexed as

Infant, Very Low Birth WeightParentsPatient DischargeAdultCase-Control StudiesChinaFemaleHumansInfant, NewbornInfant, PrematureIntensive Care Units, NeonatalMaleRetrospective Studies

Identifiers

PMID40785514
PMCPMC12336925

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.