ArticleTurkish journal of anaesthesiology and reanimation2025
Continuous Low-dose Epidural Morphine and Ketamine Analgesia Improves Quality of Recovery after Major Lumbar Spine Surgery: A Randomised Controlled Trial.
Article in Turkish journal of anaesthesiology and reanimation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Quality of Recovery (QoR)-15 Scale: From Statistical Significance to Clinical Relevance and Beyond.Turkish journal of anaesthesiology and reanimation · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: The effect of postoperative analgesia on the quality of recovery (QoR) after major lumbar spine surgery is understudied. We hypothesized that continuous epidural morphine and ketamine administration would provide effective analgesia, thereby improving QoR compared to continuous intravenous morphine and ketamine using the QoR-15 questionnaire. Methods: A total of 40 patients were randomised to receive either continuous low-dose epidural morphine and ketamine via an intraoperatively placed epidural catheter (Group A) or intravenous morphine and ketamine using a patient-controlled analgesia system (Group B) for 48 hours. All patients were anaesthetized using standard anaesthesia drugs. The primary outcome was QoR at 24 and 48 hours after surgery using the QoR-15 questionnaire. The secondary outcomes were pain score at various time points during the first 48 hours, rescue analgesic requirements, ambulation time, length of hospital stay, and patient satisfaction. Results: Forty patients were recruited (20 in each group), and all patient data were included in the analysis. The total QoR-15 scores for Group A and Group B at 24 hours were 134.8±6.65 and 128.9±6.12, respectively (P=0.006). The QoR-15 scores at 48 hours for groups A and B were 136.7±6.02 vs 132.10±6.8 (P=0.029), respectively. The pain score was lower in Group A than in Group B at rest and during movement, with P=0.015 and 0.001, respectively, and all the other secondary outcomes were comparable between the groups. Conclusion: Postoperative analgesia with continuous low-dose epidural morphine and ketamine via an intraoperatively placed epidural catheter provides superior QoR after major lumbar spine surgery as compared to intravenous morphine and ketamine.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.