Evidence map›Paper›PMID 40785216›Full record

ArticleVeterinary surgery : VS2026

Biomechanical testing of three constructs for prosthetic laryngoplasty in horses demonstrates advantages of differing metallic implants in the arytenoid cartilage.

Machiel P Ysebaert, James Johnson, Ulrika Marie, Arian Campos, Anouk Verchrerin, Norm G Ducharme, Fabrice Rossignol, Lauren K Luedke

Abstract read
In one paragraph

Article in Veterinary surgery : VS, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Machiel P YsebaertColorado State University, Veterinary Teaching Hospital, Fort Collins, Colorado, USA.
James JohnsonColorado State University, Orthopaedic Bioengineering Research Laboratory, Fort Collins, Colorado, USA.
Ulrika MarieClinique Vétérinaire equine de Grosbois, Marolles-en-Brie, France.ORCID https://orcid.org/0000-0003-4277-2538
Arian CamposClinique Vétérinaire equine de Grosbois, Marolles-en-Brie, France.ORCID https://orcid.org/0000-0001-7172-192X
Anouk VerchrerinClinique Vétérinaire equine de Grosbois, Marolles-en-Brie, France.
Norm G DucharmeDepartment of Clinical Sciences, Cornell University, College of Veterinary Medicine, Ithaca, New York, USA.
Fabrice RossignolClinique Vétérinaire equine de Grosbois, Marolles-en-Brie, France.
Lauren K LuedkeColorado State University, Veterinary Teaching Hospital, Fort Collins, Colorado, USA.

Funding

Colorado State University College Research Council Colorado Racing Commission
6 · The paper itself

Abstract

objectiveTo compare the biomechanical stability of a novel arytenoid implant (tie-bolt, TB) with a suture anchor (SA) and standard laryngoplasty using suture alone (control) in equine larynges. STUDY

designRandomized ex vivo controlled experimental study. SAMPLE POPULATION: Thirty equine cadaver larynges.

methodsLarynges were randomly assigned to TB, SA, or control groups (n = 10 each). The force of abduction was measured for each construct, then constructs underwent cyclic loading (5-50 N for 3000 cycles) to assess elongation, followed by load-to-failure testing to assess ultimate load, displacement, stiffness, and mode of failure.

resultsThe SA required less force to achieve 88% abduction (8.31 ± 2.46 N) than the TB (11.48 ± 3.6 N, p = .07) and controls (11.86 ± 2.99 N, p = .04). The TB had less construct elongation (2.62 ± 0.61 mm) than SA constructs (3.87 ± 1.25 mm, p = .01) and was stiffer (31.05 ± 3.38 N/mm) than both control (23.48 ± 2.06 N/mm, p < .0001) and SA constructs (18.53 ± 4.15 N/mm, p < .0001). The TB construct failed at higher ultimate load and displacement (367.25 ± 66.98 N and 19.11 ± 2.51 mm, respectively) than the control (238.14 ± 19.46 N and 14.23 ± 1.6 mm; p < .0001 for both) and SA constructs (196.55 ± 47.17 N and 16.23 ± 2.02 mm; p < .0001 and p = .01, respectively). The primary modes of failure were suture cut-through for control, implant pullout for SA, and arytenoid fracture for TB.

conclusionThe SA required the least force for abduction. The TB was a stiffer construct that resulted in higher failure loads. CLINICAL SIGNIFICANCE: The SA may reduce construct loading during abduction. The TB offers superior mechanical stability, potentially reducing long-term degradation from cyclic loading.

Indexed as

Arytenoid CartilageLaryngoplastyProstheses and ImplantsAnimalsBiomechanical PhenomenaCadaverHorsesRandom AllocationSuture Anchors

Identifiers

PMID40785216
PMCPMC12810437

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.