Evidence map›Paper›PMID 40785129›Full record

Trial reportJournal of periodontology2026

Volumetric buccal bone alterations at immediate implant sites with or without soft tissue augmentation: A 6-month assessment.

Mary Jung, Duong Tran, Chi-Ching Chang, Sung K Kim, Yosuke Tsukiboshi, Seiko Min, Srinivas Ayilavarapu, Chun-Teh Lee

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of periodontology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02864862 (Esthetic Outcomes Following Immediate Implant Combine With Soft Tissue Augmentation), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02864862 phase4completednot on this map

Esthetic Outcomes Following Immediate Implant Combine With Soft Tissue Augmentation

TypeinterventionalSponsorThe University of Texas Health Science Center, HoustonRan2016 to 2021Enrolled46ConditionsDental Implant, Immediate Dental Implant, Soft Tissue AugmentationArmsImmediate implant, SCTG, ADM
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mary JungDepartment of Periodontics and Dental Hygiene, The University of Texas Health Science Center at Houston School of Dentistry, Houston, Texas, USA.
Duong TranDepartment of Diagnostic and Biomedical Sciences, The University of Texas Health Science Center at Houston School of Dentistry, Houston, Texas, USA.
Chi-Ching ChangDepartment of Periodontics and Dental Hygiene, The University of Texas Health Science Center at Houston School of Dentistry, Houston, Texas, USA.
Sung K KimDepartment of Clinical Sciences, University of Nevada School of Dental Medicine, Las Vegas, Nevada, USA.
Yosuke TsukiboshiDepartment of Periodontics and Dental Hygiene, The University of Texas Health Science Center at Houston School of Dentistry, Houston, Texas, USA.ORCID https://orcid.org/0000-0002-8269-5808
Seiko MinDepartment of Periodontics and Dental Hygiene, The University of Texas Health Science Center at Houston School of Dentistry, Houston, Texas, USA.
Srinivas AyilavarapuDepartment of Periodontics and Dental Hygiene, The University of Texas Health Science Center at Houston School of Dentistry, Houston, Texas, USA.
Chun-Teh LeeDepartment of Periodontics and Dental Hygiene, The University of Texas Health Science Center at Houston School of Dentistry, Houston, Texas, USA.

Funding

Osteology Foundation, Osteology Young Researcher Grants 15-150
6 · The paper itself

Abstract

backgroundThis study is part of a randomized controlled trial investigating the impact of soft tissue augmentation (STA) using subepithelial connective tissue graft (SCTG) (immediate implant with subepithelial connective tissue graft [ICT] group) or acellular dermal matrix (ADM) (immediate implant with acellular dermal matrix [IAD] group) versus no STA (control) on the clinical outcomes following immediate implant placement (IIP). This study aimed to investigate volumetric buccal bone dimensional changes at immediate implant sites 6 months after the surgery.

methodsForty-five patients requiring extraction of a maxillary anterior tooth or premolar and randomly assigned to one of the three groups were included. Cone-beam computed tomography (CBCT) images were obtained prior to tooth extraction and 6 months after IIP and then superimposed to evaluate 3D (volumetric) and 2D (linear) changes in buccal bone dimensions around the implant. Measurements included three regions of interest (coronal, middle, and apical segments). The associations between clinical factors and 3D buccal bone dimensional changes were analyzed using linear regression analysis. The correlations between 3D and 2D measurements were analyzed using Pearson's correlation coefficient. Statistical significance was assessed using an alpha level of 0.05.

resultsVolumetric bone dimensional changes were not significantly different between the groups. The greatest amount of bone loss occurred in the coronal segment (ICT: -14.99 ± 4.29 mm

conclusionSTA did not significantly affect bone dimensional loss at 6 months. Linear measurements may not fully represent volumetric bone dimensional changes at immediate implant sites. CLINICAL

trial registrationThis study is part of a randomized controlled trial (RCT) registered with ClinicalTrials.gov (ID NCT02864862). The title of the trial is Esthetic Outcomes Following Immediate Implant Combined with Soft Tissue Augmentation. PLAIN LANGUAGE SUMMARY: This study investigated how soft tissue augmentation (STA) affected the changes in bone around dental implants placed immediately after tooth extraction. Specifically, it compared the use of a connective tissue graft and an acellular dermal matrix against no STA. Forty-five patients who needed a maxillary anterior tooth or premolar extraction and a dental implant were included. Before the extraction and 6 months after implant placement, cone-beam computed tomography (CBCT) scans were taken to measure changes in the bone dimensions around the implants. The analysis included three sections of the bone: the coronal, middle, and apical sections. The results showed no significant differences in bone changes between the different treatment groups. The greatest bone loss was found in the coronal section. Measurements taken in three dimensions (3D) and two dimensions (2D) showed varying degrees of correlation. Overall, the findings suggested that STA did not affect bone loss around dental implants, and 2D measurements may not accurately reflect the 3D changes in bone.

Indexed as

Alveolar Bone LossAlveolar ProcessImmediate Dental Implant LoadingAcellular DermisAdultBicuspidCone-Beam Computed TomographyConnective TissueDental Implantation, EndosseousFemaleFollow-Up StudiesGingivaHumansImaging, Three-DimensionalMaleMaxillabone remodelingcone‐beam computed tomographydental implantsrandomized controlled trialsingle tooth

Identifiers

PMID40785129
PMCPMC13001143

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.