Evidence map›Paper›PMID 40785052›Full record

ArticleChannels (Austin, Tex.)2025

BK channel activity in skin fibroblasts from patients with neurological disorder.

Ria L Dinsdale, Thomas R Middendorf, Deborah Disilvestre, David Adams, William Gahl, Ellen F Macnamara, Lynne Wolfe, Camilo Toro, Cynthia J Tifft, Andrea L Meredith

Abstract read
In one paragraph

Article in Channels (Austin, Tex.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ria L DinsdaleDepartment of Physiology, University of Maryland School of Medicine, Baltimore, MD, USA.ORCID 0000-0003-1384-5582
Thomas R MiddendorfDepartment of Neuroscience and Center for Learning and Memory, University of Texas at Austin, Austin, TX, USA.ORCID 0000-0002-7179-291X
Deborah DisilvestreDepartment of Physiology, University of Maryland School of Medicine, Baltimore, MD, USA.
David AdamsNIH Undiagnosed Diseases Program, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA.ORCID 0000-0002-6660-1242
William GahlNIH Undiagnosed Diseases Program, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA.ORCID 0000-0002-2494-6752
Ellen F MacnamaraNIH Undiagnosed Diseases Program, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA.ORCID 0000-0002-9418-3287
Lynne WolfeNIH Undiagnosed Diseases Program, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA.ORCID 0000-0001-7628-5741
Camilo ToroNIH Undiagnosed Diseases Program, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA.ORCID 0000-0002-3917-9031
Cynthia J TifftNIH Undiagnosed Diseases Program, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA.ORCID 0000-0002-3931-1207
Andrea L MeredithDepartment of Physiology, University of Maryland School of Medicine, Baltimore, MD, USA.ORCID 0000-0003-1061-2302

Funding

ASCEND Training Model to Increase Diversity in the Biomedical Research WorkforceRL5GM118972 · NIGMS · MORGAN STATE UNIVERSITY · PI HOHMANN, CHRISTINE F, SHEIKHATTARI, PAYAM · 2015 to 2023
$8.1M
Daily Regulation of Ionic CurrentsR01HL102758 · NHLBI · UNIVERSITY OF MARYLAND BALTIMORE · PI LEDERER, WILLIAM JONATHAN · 2010 to 2024
$6.3M
NHLBI NIH HHS R01 HL102758NIGMS NIH HHS RL5 GM118972
6 · The paper itself

Abstract

Seventy-five unique variants in the

Indexed as

FibroblastsLarge-Conductance Calcium-Activated Potassium Channel alpha SubunitsLarge-Conductance Calcium-Activated Potassium ChannelsNervous System DiseasesSkinFemaleHumansMaleKCNMA1 protein, humanLarge-Conductance Calcium-Activated Potassium Channel alpha SubunitsLarge-Conductance Calcium-Activated Potassium ChannelsBK channelcalcium-activated potassium channelchannelopathyKCa1.1KCNMA1slowpoke

Identifiers

PMID40785052
PMCPMC12341059

What OpenQuestion holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.