Evidence map›Paper›PMID 40784995›Full record

ArticleCell and tissue banking2025

Impact of the COVID-19 pandemic on the operations of one regional musculoskeletal tissue bank.

Francesco Puglia, Andrea Della Valle, Riccardo Compagnoni, Daniele Priano, Alessandra Menon, Lorenzo Teani, Giovanni Andrea La Maida, Marco Sacchi, Federico Ambrogi, Pietro Simone Randelli

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Article in Cell and tissue banking, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Francesco PugliaU.O.C. Ortopedia e Traumatologia Pediatrica, ASST Gaetano Pini/CTO, Piazza Cardinal Ferrari 1, 20122, Milan, Italy. Francesco.puglia@gmail.com.
Andrea Della ValleBanca del Tessuto Muscolo-scheletrico Regione Lombardia, ASST Gaetano Pini/CTO, Piazza Cardinal Ferrari 1, 20122, Milan, Italy.
Riccardo CompagnoniU.O.C. 1° Clinica Ortopedica, ASST Gaetano Pini/CTO, Piazza Cardinal Ferrari 1, 20122, Milan, Italy.
Daniele PrianoU.O.C. Ortopedia e Traumatologia Pediatrica, ASST Gaetano Pini/CTO, Piazza Cardinal Ferrari 1, 20122, Milan, Italy.
Alessandra MenonU.O.C. 1° Clinica Ortopedica, ASST Gaetano Pini/CTO, Piazza Cardinal Ferrari 1, 20122, Milan, Italy.
Lorenzo TeaniU.O.C. 1° Clinica Ortopedica, ASST Gaetano Pini/CTO, Piazza Cardinal Ferrari 1, 20122, Milan, Italy.
Giovanni Andrea La MaidaU.O.C. Patologie Vertebrali e Scoliosi, ASST Gaetano Pini/CTO, Piazza Cardinal Ferrari 1, 20122, Milan, Italy.
Marco SacchiS.C. Trapianti Lombardia- NITp, IRCCS Fondazione Ca'Granda Ospedale Maggiore Policlinico di Milano, Via Francesco Sforza 35, 20122, Milan, Italy.
Federico AmbrogiLaboratory of Medical Statistics, Biometry and Epidemiology ''G.A. Maccaro'', Department of Clinical Sciences and Community Health, Università degli Studi di Milano, Milan, Italy.
Pietro Simone RandelliU.O.C. 1° Clinica Ortopedica, ASST Gaetano Pini/CTO, Piazza Cardinal Ferrari 1, 20122, Milan, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The study explores the effects of the COVID-19 pandemic on the Musculoskeletal Tissue Bank (MSTB) in Milan, with a particular focus on tissue harvesting and its subsequent use in surgical procedures. A retrospective descriptive epidemiological analysis compared data from the pre-pandemic period (2018-2019) with that of the pandemic period (2020-2022), revealing a 24.8% reduction in tissue retrievals during the pandemic. Although there was a decrease in the number of eligible donors not collected (from 93 to 67, from 36.05 to 34.54%), this reduction was not statistically significant. The decline in tissue retrievals was due to decreased non-COVID-related pathologies, a lower number of potential donors from reduced accidents and increase in COVID-positive deaths. However, the MSTB successfully met tissue demands throughout this period. Notably, the reduction in retrievals at the MSTB was lower than national averages (- 24.8 vs. - 47.5%). Logistic regression analysis showed no significant organizational issues in donor collection. Despite the challenges, the MSTB remained resilient and adaptable, continuing its essential services. This underscores the broader impact of the pandemic on healthcare systems and emphasizes the importance of a flexible healthcare infrastructure during public health emergencies.

Indexed as

COVID-19Musculoskeletal SystemTissue BanksHumansItalyMalePandemicsRetrospective StudiesSARS-CoV-2Tissue and Organ HarvestingTissue and Organ ProcurementTissue DonorsBone bankCovid-19GraftsOrthopaedic surgeryTissue

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.