ReviewEnvironmental microbiology reports2025
Strengthen or Weaken: Evolutionary Directions of Cross-Feeding After Formation.
Review in Environmental microbiology reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Emergent phenotypic heterogeneity in synthetic cross-feeding consortia driven by heterogeneous metabolite distribution.National science review · 2026Article
- Low initial metabolite production enhances stability in syntrophic bacterial consortia.Communications biology · 2026Article
- Advances, opportunities, and challenges in microbial community construction: from environmental remediation to biomanufacturing.Archives of microbiology · 2026Review
- Strengthen or Weaken: Evolutionary Directions of Cross-Feeding After Formation.Environmental microbiology reports · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Interactions between species and the evolution of strains are important biotic factors determining the microbial community dynamics, with these two processes being deeply intertwined. Cross-feeding is a prevailing mutualistic interaction in natural microbial communities in which metabolites secreted by one microbe can be utilised by another. Constructing synthetic microbial consortia based on cross-feeding is a promising strategy for bioremediation and bioproduction. But how to improve the performance and the stability of consortia remains a challenge. This review discusses the features of two opposite evolutionary directions of cross-feeding consortia over time, providing insights into the factors affecting the evolutionary process. While coevolving, cross-feeding may strengthen with stronger metabolic coupling, deeper growth dependence, and/or deeper evolutionary dependence; then the consortia become reinforced. Conversely, unsuitable environmental conditions can lead to the direct collapse of the cross-feeding consortia due to metabolic decoupling, partner extinction, or cheater dominance. The loss of the fitness advantage and the constraints on the evolutionary ability can also lead to the weakening of cross-feeding. Cross-feeding partners can affect the evolution of focal strains from different aspects, such as niche space, selective pressure, horizontal gene transfer, and evolutionary rate. Analysing cross-feeding from an evolutionary perspective will advance our understanding of microbial community dynamics and enable rational designs of efficient and stable synthetic microbial consortia.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.