Evidence map›Paper›PMID 40783911›Full record

ReviewPharmacology research & perspectives2025

Mangiferin Against Respiratory Diseases: Pharmacological Targets and Prospects.

Kazi Ahsan Ahmed, Nusrat Afrin, Popy Ghosh, Irin Amin Heya, Sajidur Rahman Akash, Akhi Moni, Mohammad Nazrul Islam, Md Golzar Hossain, Alessandra Sinopoli, Md Abdul Hannan and 1 more

Abstract readReview
In one paragraph

Review in Pharmacology research & perspectives, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Kazi Ahsan AhmedABEx Bio-Research Center, Dhaka, Bangladesh.ORCID 0000-0002-4831-7758
Nusrat AfrinABEx Bio-Research Center, Dhaka, Bangladesh.
Popy GhoshDepartment of Biochemistry and Molecular Biology, Bangladesh Agricultural University, Mymensingh, Bangladesh.
Irin Amin HeyaABEx Bio-Research Center, Dhaka, Bangladesh.
Sajidur Rahman AkashABEx Bio-Research Center, Dhaka, Bangladesh.
Akhi MoniABEx Bio-Research Center, Dhaka, Bangladesh.
Mohammad Nazrul IslamABEx Bio-Research Center, Dhaka, Bangladesh.
Md Golzar HossainDepartment of Microbiology and Hygiene, Bangladesh Agricultural University, Mymensingh, Bangladesh.
Alessandra SinopoliDepartment of Prevention, Local Health Authority Roma 1, Rome, Italy.
Md Abdul HannanDepartment of Biochemistry and Molecular Biology, Bangladesh Agricultural University, Mymensingh, Bangladesh.
Md Jamal UddinABEx Bio-Research Center, Dhaka, Bangladesh.ORCID 0000-0003-2911-3255

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Respiratory diseases are associated with high mortality worldwide. Respiratory infections can lead to the emergence of chronic respiratory diseases. Scientists are constantly striving to identify new therapies with reduced side effects. The rise of antibiotic resistance and the scarcity of effective treatments further necessitate the development of novel therapeutics specific to respiratory diseases. Extensive research has been conducted on natural products that could be effective against respiratory diseases. Mangiferin, a polyphenol with a C-glycosyl xanthone structure, is a bioactive phytochemical that has potential applications in the treatment of respiratory tract infections. Mangiferin could be a therapeutic option against respiratory diseases because of its ability to target a variety of pharmacological pathways implicated in the development of these infections. It has been shown to limit infections, lower inflammation, control immune responses, and enhance host defense mechanisms. This review provides comprehensive insight into mangiferin's potential against various respiratory disorders, focusing on its pharmacological activity and therapeutic prospects. Despite the potential of mangiferin against respiratory problems-related pathobiology, additional scientific validation through clinical trials is required before the clinical application of mangiferin in the management of respiratory diseases.

Indexed as

Respiratory Tract DiseasesRespiratory Tract InfectionsXanthonesAnimalsHumansmangiferinXanthonesfibrosisinfectionsinflammationMangiferinoxidative stressrespiratory diseases

Identifiers

PMID40783911
PMCPMC12335824

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.