Evidence map›Paper›PMID 40783819›Full record

ArticleThe FEBS journal2025

Defining the interactome of the pancreas-specific SPCA2 isoform (SPCA2C) identifies unique links to store-operated Ca

Petra Samardzija, Melissa A Fenech, Oneeb Hassan, Ryann Lang, McKenzie C Carter, Stephanie Chen, Selina Shi, Rithwik Ramachandran, Peter B Stathopulos, Christopher L Pin

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The FEBS journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Petra SamardzijaDepartment of Physiology and Pharmacology, Schulich School of Medicine & Dentistry, University of Western Ontario, London, Canada.
Melissa A FenechDepartment of Physiology and Pharmacology, Schulich School of Medicine & Dentistry, University of Western Ontario, London, Canada.
Oneeb HassanDepartment of Physiology and Pharmacology, Schulich School of Medicine & Dentistry, University of Western Ontario, London, Canada.
Ryann LangDepartment of Physiology and Pharmacology, Schulich School of Medicine & Dentistry, University of Western Ontario, London, Canada.
McKenzie C CarterDepartment of Physiology and Pharmacology, Schulich School of Medicine & Dentistry, University of Western Ontario, London, Canada.
Stephanie ChenDepartment of Physiology and Pharmacology, Schulich School of Medicine & Dentistry, University of Western Ontario, London, Canada.
Selina ShiDepartment of Physiology and Pharmacology, Schulich School of Medicine & Dentistry, University of Western Ontario, London, Canada.
Rithwik RamachandranDepartment of Physiology and Pharmacology, Schulich School of Medicine & Dentistry, University of Western Ontario, London, Canada.ORCID https://orcid.org/0000-0001-9557-9905
Peter B StathopulosDepartment of Physiology and Pharmacology, Schulich School of Medicine & Dentistry, University of Western Ontario, London, Canada.
Christopher L PinDepartment of Physiology and Pharmacology, Schulich School of Medicine & Dentistry, University of Western Ontario, London, Canada.ORCID https://orcid.org/0000-0002-1245-1058

Funding

Natural Sciences and Engineering Research Council of Canada RGPIN-2024-06525
6 · The paper itself

Abstract

Calcium (Ca

Indexed as

CalciumCalcium SignalingCalcium-Transporting ATPasesPancreasEndoplasmic ReticulumHEK293 CellsHumansORAI1 ProteinProtein IsoformsStromal Interaction Molecule 1ATP2C2 protein, humanCalciumCalcium-Transporting ATPasesORAI1 ProteinORAI1 protein, humanProtein IsoformsStromal Interaction Molecule 1calciumcalcium release‐activated calcium channel protein 1coiled‐coil domain‐containing protein 47secretory pathway calcium‐ATPase 2Cstore‐operated calcium entrystromal interaction molecule 1

Identifiers

PMID40783819
PMCPMC12713332

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.