Evidence map›Paper›PMID 40783463›Full record

ArticleSpinal cord2025

Increased risk of osteoarthritis in persons with spinal cord injury: a population-based longitudinal follow-up study in Taiwan.

Chien-Po Liu, Shin-Liang Pan

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Article in Spinal cord, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Chien-Po LiuDepartment of Physical Medicine and Rehabilitation, National Taiwan University Hospital, Taipei, Taiwan.
Shin-Liang PanDepartment of Physical Medicine and Rehabilitation, National Taiwan University Hospital, Taipei, Taiwan. panslcb@gmail.com.ORCID 0000-0001-6451-4666

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

STUDY

designRetrospective cohort study.

objectivesTo assess the relative risk of osteoarthritis (OA) in individuals with newly diagnosed spinal cord injury (SCI) compared to a matched non-SCI group.

settingTaiwan's Longitudinal Health Insurance Database.

methodsWe identified 1373 individuals aged 20-69 years with newly diagnosed SCI between 2002 and 2005 as the SCI group. A propensity-score-matched non-SCI group (N = 5492) with similar baseline demographic and clinical characteristics was selected for comparison. Both groups were followed until December 2011. OA-free survival was analyzed via Kaplan-Meier curves, and the association between SCI and OA risk was evaluated via stratified Cox proportional-hazards regression. To assess temporal risk variations, we performed landmark analysis with a 1-year cutoff, dividing follow-up into early (0-1 year) and long-term (≥1 year) periods.

resultsThe respective incidence rates of OA for the SCI and non-SCI groups were 45.4 per 1000 person-years (95% confidence interval [CI], 40.1-50.1) and 31.6 per 1000 person-years (95% CI, 29.8-33.4). The hazard ratio of OA for the SCI group, as compared to the non-SCI group, was 1.52 (95% CI 1.34-1.72, p < 0.0001).

conclusionsThis population-based longitudinal follow-up study indicates that there is an increased long-term risk of OA in persons with SCI, underscoring the need for clinical vigilance and early diagnostic measures in this population. Further research is needed to explore the mechanisms underlying the association between these two conditions.

Indexed as

OsteoarthritisSpinal Cord InjuriesAdultAgedFemaleFollow-Up StudiesHumansIncidenceKaplan-Meier EstimateLongitudinal StudiesMaleMiddle AgedProportional Hazards ModelsRetrospective StudiesRisk FactorsTaiwan

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.