Evidence map›Paper›PMID 40783460›Full record

ArticleScientific reports2025

The ocular shape and retinal structure in children with a history of treated retinopathy of prematurity.

Tomo Nishi, Yutaro Mizusawa, Hiroto Terasaki, Taiji Sakamoto, Nahoko Ogata, Tetsuo Ueda

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In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Tomo NishiDepartment of Ophthalmology, Nara Medical University, 840 Kashihara City, Kashihara, Nara, 634-8522, Nara, Japan. tomon@naramed-u.ac.jp.
Yutaro MizusawaDepartment of Ophthalmology, Nara Medical University, 840 Kashihara City, Kashihara, Nara, 634-8522, Nara, Japan.
Hiroto TerasakiDepartment of Ophthalmology, Kagoshima University, Kagoshima, Japan.
Taiji SakamotoDepartment of Ophthalmology, Kagoshima University, Kagoshima, Japan.
Nahoko OgataDepartment of Ophthalmology, Nara Medical University, 840 Kashihara City, Kashihara, Nara, 634-8522, Nara, Japan.
Tetsuo UedaDepartment of Ophthalmology, Nara Medical University, 840 Kashihara City, Kashihara, Nara, 634-8522, Nara, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study compared the retinal structure between the eyes of children with a history of treated retinopathy of prematurity (ROP), spontaneously regressed ROP and full-term children using widefield optical coherence tomography angiography (OCTA) and swept-source OCT (SSOCT). We identified patients who were diagnosed with ROP and followed up. Age-matched full-term controls were also recruited. We reviewed the medical records of 34 ROP eyes (34 patients) treated with laser photocoagulation, 5 spontaneously regressed ROP eyes (5 patients), and 15 age-matched full-term controls (15 control eyes). The thickness of the foveal retina and choroid, the foveal avascular zone (FAZ), and ocular shape were assessed using OCTA and SSOCT (Xephilio OCT-S1) images. The mean foveal thickness of the treated ROP eyes was significantly thicker than that of the control eyes. The FAZ of the treated ROP eyes was significantly smaller than that of the control eyes. SSOCT images revealed that 5 of 34 eyes in the treated ROP group had a dome-shaped macula, while 18 had an elongated barrel shape. Understanding these structural changes is crucial for developing targeted treatments and optimizing visual function in this population.

Indexed as

RetinaRetinopathy of PrematurityCase-Control StudiesChildChild, PreschoolFemaleFovea CentralisHumansInfantInfant, NewbornLaser CoagulationMaleTomography, Optical CoherenceLaser treatmentRetinopathy of prematuritySwept-source OCTWidefield optical coherence tomography angiography

Identifiers

PMID40783460
PMCPMC12335439

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.