Evidence map›Paper›PMID 40783449›Full record

ArticleScientific reports2025

Effects of different solvents on phytochemical constituents, in-vitro antimicrobial activity, and volatile components of Boehmeria rugulosa Wedd. wood extract.

Priyanka Arya, Devina Vaidya, Manisha Kaushal, Sunita Devi, Anil Gupta, Subhash Chand

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Priyanka AryaDepartment of Food Science and Technology, Dr. YS Parmar University of Horticulture and Forestry Nauni, Solan, India. arya.priyanka32@gmail.com.
Devina VaidyaDepartment of Food Science and Technology, Dr. YS Parmar University of Horticulture and Forestry Nauni, Solan, India.
Manisha KaushalDepartment of Food Science and Technology, Dr. YS Parmar University of Horticulture and Forestry Nauni, Solan, India.
Sunita DeviDepartment of Basic Sciences, Dr. YS Parmar University of Horticulture and Forestry Nauni, Solan, India.
Anil GuptaDepartment of Food Science and Technology, Dr. YS Parmar University of Horticulture and Forestry Nauni, Solan, India.
Subhash ChandDepartment of Basic Sciences, Dr. YS Parmar University of Horticulture and Forestry Nauni, Solan, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study investigates the effects of various solvents on the phytochemical composition, in-vitro antimicrobial activity, and volatile constituents of Boehmeria rugulosa Wedd. wood extract. Phytochemical screening revealed significant variations in the concentration of bioactive compounds depending on the extraction solvent. Methanolic, ethanolic, and aqueous extracts exhibited distinct profiles of alkaloids, flavonoids, phenolics, and tannins, with notable differences in their respective bioactive contents. Among the tested solvents, 70% aqueous ethanol yielded the highest extract recovery, containing total phenols (229.3 mg GAE/g) and total flavonoids (67.13 mg QE/g). Gas Chromatography-Mass Spectrometry (GC-MS) identified 14 volatile compounds, including terpenoids, aldehydes, ketones, and phenolic derivatives, with clear solvent-dependent variations. In-vitro antimicrobial assays indicated that the ethanolic extract exhibited the strongest antibacterial activity, while the aqueous extract showed moderate antifungal activity. The 70% aqueous ethanol extract demonstrated significant antibacterial efficacy against Staphylococcus aureus ATCC 12,600 (18.45 mm), Bacillus cereus ATCC 6633 (15.88 mm), and Escherichia coli ATCC 1041 (12.35 mm). These findings highlight the critical role of solvent polarity in optimizing the extraction of bioactive and antimicrobial compounds from B. rugulosa wood, with implications for the development of plant-based therapeutic agents and natural preservative systems.

Indexed as

Anti-Infective AgentsPhytochemicalsPlant ExtractsSolventsVolatile Organic CompoundsWoodZingiberaceaeAnti-Bacterial AgentsFlavonoidsGas Chromatography-Mass SpectrometryMicrobial Sensitivity TestsPhenolsStaphylococcus aureusAnti-Bacterial AgentsAnti-Infective AgentsFlavonoidsPhenolsPhytochemicalsPlant ExtractsSolventsVolatile Organic CompoundsFermented foodsGC–MSPhytochemicalsTotal phenolic content

Identifiers

PMID40783449
PMCPMC12335597

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.