Evidence map›Paper›PMID 40782336›Full record

Observational studyFuture oncology (London, England)2025

Postoperative nomogram for predicting involved lymph node in differentiated thyroid carcinoma: an observational study.

Yunbo Li, Junyan Wang, Jinzi Hui, Guangdong Hou, Wei He, Tao Sun, Liuyan Gao, Yixin Wei, Wei Zhang, Long Zheng and 2 more

Abstract readObservational Study
In one paragraph

Observational study in Future oncology (London, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Yunbo LiDepartment of Nuclear Medicine, Tangdu Hospital, Air Force Medical University, Xi'an, China.ORCID 0000-0003-1695-8443
Junyan WangDepartment of Nuclear Medicine, Tangdu Hospital, Air Force Medical University, Xi'an, China.ORCID 0009-0000-3400-2686
Jinzi HuiDepartment of Nuclear Medicine, Shaanxi Provincial Tumor Hospital, Xi'an, China.ORCID 0000-0002-2623-4652
Guangdong HouDepartment of Urology, Tangdu Hospital, Air Force Medical University, Xi'an, China.ORCID 0000-0001-8910-5949
Wei HeDepartment of Nuclear Medicine, Tangdu Hospital, Air Force Medical University, Xi'an, China.ORCID 0000-0003-3785-4766
Tao SunDepartment of Nuclear Medicine, Tangdu Hospital, Air Force Medical University, Xi'an, China.ORCID 0009-0000-6734-8405
Liuyan GaoDepartment of Nuclear Medicine, Tangdu Hospital, Air Force Medical University, Xi'an, China.
Yixin WeiDepartment of Nuclear Medicine, Tangdu Hospital, Air Force Medical University, Xi'an, China.ORCID 0000-0002-9684-0113
Wei ZhangDepartment of Nuclear Medicine, Tangdu Hospital, Air Force Medical University, Xi'an, China.ORCID 0000-0003-0401-0591
Long ZhengDepartment of Nuclear Medicine, The Second Affiliated Hospital of Xi 'an Jiaotong University, Xi'an, China.ORCID 0000-0002-5877-6368
Peng YuanDepartment of Nuclear Medicine, Tangdu Hospital, Air Force Medical University, Xi'an, China.ORCID 0000-0001-7675-9898
Menghui YuanDepartment of Nuclear Medicine, Tangdu Hospital, Air Force Medical University, Xi'an, China.ORCID 0000-0001-9503-5975

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study aims to develop a comprehensive nomogram to accurately predict differentiated thyroid cancer (DTC) involved lymph node, enabling the personalization of treatment plans and optimizing patient outcomes.

methodsThe nomogram was developed through an analysis of data obtained from derivation cohorts. To identify independent predictors of involved lymph node, we utilized the Least Absolute Shrinkage and Selection Operator (LASSO) method in conjunction with multivariable logistic regression. These predictive factors were subsequently integrated into the nomogram's design. To ensure the tool's robustness and clinical applicability, we assessed its discriminative ability, calibration, and clinical utility in both the derivation cohort and an independent validation cohort.

resultsThe identification of four key parameters - Thyroglobulin, Lymphocyte count, BRAF

conclusionPeripheral lymphocyte counts have been found to correlate with involved lymph node in DTC patients. A nomogram tailored specifically for predicting involved lymph node in DTC guides personalized postoperative radioactive iodine (RAI) and plays a critical role in the preoperative assessment.

Indexed as

Lymph NodesNomogramsThyroid NeoplasmsAdultAgedFemaleHumansIodine RadioisotopesLymphatic MetastasisLymphocyte CountMaleMiddle AgedPostoperative PeriodPrognosisProto-Oncogene Proteins B-rafThyroglobulinBRAF protein, humanIodine RadioisotopesProto-Oncogene Proteins B-rafThyroglobulinDifferentiated thyroid cancerinvolved lymph nodelymphocyte countsnomogram,radioactive iodine

Identifiers

PMID40782336
PMCPMC12408050

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.