Evidence map›Paper›PMID 40782170›Full record

ArticleTAG. Theoretical and applied genetics. Theoretische und angewandte Genetik2025

McATL43 encoding a RING-H2 finger E3 ubiquitin ligase is responsible for Shark teeth (St) fruit wart in bitter gourd (Momordica charantia L.).

Feifan Chen, Yuehong Ding, Yiwei Wen, Xuzhen Li, Silin Wu, Xuanyu Chen, Shihan Zeng, Xiaobin Zhang, Jiayu Liu, Libo Tian and 1 more

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Article in TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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11 authors.

Feifan ChenSanya Institute of Breeding and Multiplication & School of Life and Health Sciences, Hainan University, Haikou, 570228, China.ORCID http://orcid.org/0000-0003-3634-9493
Yuehong DingSanya Institute of Breeding and Multiplication & School of Life and Health Sciences, Hainan University, Haikou, 570228, China.
Yiwei WenSanya Institute of Breeding and Multiplication & School of Life and Health Sciences, Hainan University, Haikou, 570228, China.
Xuzhen LiSanya Institute of Breeding and Multiplication & School of Life and Health Sciences, Hainan University, Haikou, 570228, China.
Silin WuKey Laboratory for Quality Regulation of Tropical Horticultural Plants of Hainan Province, School of Tropical Agriculture and Forestry, Hainan University, Danzhou, 571737, China.
Xuanyu ChenSanya Institute of Breeding and Multiplication & School of Life and Health Sciences, Hainan University, Haikou, 570228, China.
Shihan ZengSanya Institute of Breeding and Multiplication & School of Life and Health Sciences, Hainan University, Haikou, 570228, China.
Xiaobin ZhangKey Laboratory for Quality Regulation of Tropical Horticultural Plants of Hainan Province, School of Tropical Agriculture and Forestry, Hainan University, Danzhou, 571737, China.
Jiayu LiuKey Laboratory for Quality Regulation of Tropical Horticultural Plants of Hainan Province, School of Tropical Agriculture and Forestry, Hainan University, Danzhou, 571737, China.
Libo TianSanya Institute of Breeding and Multiplication & School of Life and Health Sciences, Hainan University, Haikou, 570228, China. 990917@hainanu.edu.cn.ORCID http://orcid.org/0009-0008-9519-099X
Sang ShangSanya Institute of Breeding and Multiplication & School of Life and Health Sciences, Hainan University, Haikou, 570228, China. shangsang@hainanu.edu.cn.

Funding

Hainan Provincial Major Science and Technology Project ZDKJ2021010Hainan Provincial Natural Science Foundation 322MS030Hainan Provincial Natural Science Foundation 322RC576Hainan Provincial Undergraduate Innovation Training Project S202410589031Hainan Provincial Winter Melon and Vegetable Industry Technology System-Germplasm Innovation Post HNARS-05-G01Hainan University Startup Fund RZ2300002733Hainan University Startup Fund XJ2400005243National Natural Science Foundation of China 32060682National Natural Science Foundation of China (NSFC) Youth Science Fund Project 32402567the Hainan Provincial Natural Science Foundation of China 325RC666
6 · The paper itself

Abstract

key messageFine mapping and cloning identified a 2-bp deletion within the McATL43 gene, which encodes a RING-H2 finger E3 ubiquitin ligase, resulting in a loss-of-function mutation and smooth fruit wart phenotype in bitter gourd. Fruit wart morphology, defined by the size and arrangement of ridges and tubercles, significantly affects the commercial value of bitter gourd (Momordica charantia L.). Through QTL mapping using accessions that differ in fruit wart feature, we previously identified two major loci, fwf4.1 and fwf6.1, which together explain most of the phenotypic variation. Here, we show that fwf6.1 dominantly controls a tooth-shaped wart pattern, and therefore is named Shark teeth (St). Using a segregating BC

Indexed as

FruitMomordica charantiaPlant ProteinsUbiquitin-Protein LigasesAllelesChromosome MappingPhenotypeQuantitative Trait LociPlant ProteinsUbiquitin-Protein Ligases

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.