Evidence map›Paper›PMID 40782158›Full record

SynthesisEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2025

A systematic evaluation of clinical practice guidelines for the treatment and management of vestibular schwannoma.

Najm S Khan, Samantha M Shave, Josephine Alegun, Jonathan P Kuriakose, Phillip Ashley Wackym, Scott B Shapiro

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Najm S KhanDepartment of Head and Neck Surgery & Communication Sciences, Rutgers Robert Wood Johnson Medical School, 210 Somerset Street, 11th Floor, New Brunswick, NJ, 08901, USA.ORCID http://orcid.org/0000-0003-2701-4798
Samantha M ShaveDepartment of Head and Neck Surgery & Communication Sciences, Rutgers Robert Wood Johnson Medical School, 210 Somerset Street, 11th Floor, New Brunswick, NJ, 08901, USA.ORCID http://orcid.org/0000-0002-8161-2142
Josephine AlegunDepartment of Head and Neck Surgery & Communication Sciences, Rutgers Robert Wood Johnson Medical School, 210 Somerset Street, 11th Floor, New Brunswick, NJ, 08901, USA.ORCID http://orcid.org/0009-0004-3810-5980
Jonathan P KuriakoseDepartment of Head and Neck Surgery & Communication Sciences, Rutgers Robert Wood Johnson Medical School, 210 Somerset Street, 11th Floor, New Brunswick, NJ, 08901, USA.
Phillip Ashley WackymDepartment of Head and Neck Surgery & Communication Sciences, Rutgers Robert Wood Johnson Medical School, 210 Somerset Street, 11th Floor, New Brunswick, NJ, 08901, USA.ORCID http://orcid.org/0000-0002-2904-5072
Scott B ShapiroDepartment of Head and Neck Surgery & Communication Sciences, Rutgers Robert Wood Johnson Medical School, 210 Somerset Street, 11th Floor, New Brunswick, NJ, 08901, USA. scott.shapiro@rutgers.edu.ORCID http://orcid.org/0000-0002-3658-9457

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveSystematically appraise the quality of clinical practice guidelines (CPGs) for vestibular schwannoma treatment and management by utilizing the Appraisal of Guidelines for Research and Evaluation (AGREE II) instrument.

methodsA systematic search of CPGs for the treatment and management of vestibular schwannoma was conducted. MEDLINE (PubMed), EMBASE, and Scopus were queried from inception to January 2023. Inclusion criteria was national and international guidelines or consensus statements. Data was extracted from included articles and four reviewers independently evaluated guidelines in the 6 domains of the AGREE II tool. A domain score was generated with a satisfactory threshold being ≥ 60%.

results785 articles were screened with 9 CPGs selected for evaluation. Three CPGs were found to be "high" quality, five "average" quality, and one "low" quality. CPGs overall scored highest in the "Scope and Purpose" (domain score: 93.67 ± 7.58) and "Clarity and Presentation" (89.04 ± 13.13), while "Applicability" (40.86 ± 25.27) and "Stakeholder Involvement" (57.56 ± 22.08) had the lowest scores. The level of agreement between reviewers was high, with intraclass correlation coefficients ranging from 0.91-0.98 across domains.

conclusionThis appraisal demonstrated an average to high quality for most CPGs regarding vestibular schwannoma treatment and management. While these findings suggest most CPGs are at least average quality, there are opportunities for improvement in several aspects, particularly in domains of applicability, clarifying of conflicts of interest, strength of methodology, and stakeholder involvement.

Indexed as

Neuroma, AcousticPractice Guidelines as TopicHumansAcoustic neuromaAGREE IIClinical practice guidelinesGuideline appraisalVestibular schwannoma

Identifiers

PMID40782158

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.