Evidence map›Paper›PMID 40782154›Full record

Observational studyEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2025

Long-term clinical control in chronic rhinosinusitis: Outcomes more than five years after surgery.

Gonneke E Joustra, Marc C den Heijer, Rahma Q H Al Yousef, Karin M Vermeulen, György B Halmos, Astrid G W Korsten-Meijer, Robert A Feijen

Abstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Gonneke E JoustraDepartment of Otorhinolaryngology - Head and Neck Surgery, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands. g.e.joustra@umcg.nl.ORCID http://orcid.org/0000-0001-8171-0546
Marc C den HeijerDepartment of Otorhinolaryngology - Head and Neck Surgery, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.ORCID http://orcid.org/0000-0002-0425-613X
Rahma Q H Al YousefDepartment of Otorhinolaryngology - Head and Neck Surgery, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.ORCID http://orcid.org/0009-0008-2739-2258
Karin M VermeulenDepartment of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.ORCID http://orcid.org/0000-0001-9257-2791
György B HalmosDepartment of Otorhinolaryngology - Head and Neck Surgery, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.ORCID http://orcid.org/0000-0003-2460-2260
Astrid G W Korsten-MeijerDepartment of Otorhinolaryngology - Head and Neck Surgery, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.ORCID http://orcid.org/0000-0001-5094-7698
Robert A FeijenDepartment of Otorhinolaryngology - Head and Neck Surgery, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.ORCID http://orcid.org/0000-0002-8568-0847

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeChronic rhinosinusitis (CRS) is a common chronic and disabling disease with a high socioeconomic burden. The primary goal of treatment is improving health-related quality of life (HRQoL) and maintaining clinical control. The aim of this study was to assess clinical control in CRS patients more than 5 years after endoscopic endonasal surgery (EES).

methodsIn this observational cohort study, 123 patients with CRS were included and they completed the Endoscopic Endonasal Sinus and Skull Base Surgery Questionnaire and updated European Position Paper on Rhinosinusitis and Nasal Polyps (EPOS) criteria. Three clinical control groups were obtained according to the EPOS criteria and corresponding EES-Q and domain scores were analyzed. Univariate analyses were performed to identify variables significantly associated with outcome.

resultsSymptoms of 25.2% of CRS patients were 'controlled', 26.8% were 'partly controlled' and 48.0% were 'uncontrolled' according to the EPOS criteria. Nonsteroidal anti-inflammatory drug - exacerbated respiratory disease, allergic rhinitis, revision surgery, smoking, asthma, and nasal polyps were all significantly associated with partly controlled or uncontrolled CRS. The physical domain played the most significant role in disease control, followed by the social and psychological domain.

conclusionAccording to the updated EPOS criteria, only 25% of patients had controlled CRS more than five years following EES. This emphasizes the importance of unravelling the factors that contribute to disease control to improve treatment. The multidimensional aspect should be taken into account as well as the patients' perspective. LEVEL OF EVIDENCE: IIB.

Indexed as

EndoscopyQuality of LifeRhinitisSinusitisAdultAgedChronic DiseaseFemaleFollow-Up StudiesHumansMaleMiddle AgedNasal PolypsRhinosinusitisSurveys and QuestionnairesTreatment OutcomeChronic rhinosinusitisClinical controlDisease controlEES-QPatient-reported outcome measureQuality of life

Identifiers

PMID40782154
PMCPMC12423212

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.