ArticleClinical oral investigations2025
Impact of bleaching on white spot lesions: hydrogen peroxide permeability and color alteration.
Article in Clinical oral investigations, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- In Vitro Effects of Combining Resin Infiltration and At-Home Bleaching on Hydrogen Peroxide Penetration, Color Change and Enamel Morphology.Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.] · 2026Article
- Synthesis, characterization and evaluation of novel bleaching gels containing bioactive glass and nano-hydroxyapatite on hydrogen peroxide diffusion, bleaching efficacy and enamel protection.Clinical oral investigations · 2025Article
- Assessing Esthetic and Functional Benefits of Three Types of Maxillary Partial Denture Designs over Five Years.Dentistry journal · 2025Article
- Resin infiltration and in-office dental bleaching on different substrates: hydrogen peroxide penetration, color change, and enamel morphology- an in vitro study.Clinical oral investigations · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
objectivesTo assess the penetration of hydrogen peroxide (HP) into the pulp chamber and the bleaching efficacy on teeth with white spot lesions (WSLs) compared to sound teeth, when subjected to both in-office and at-home bleaching treatments. MATERIALS AND
methodsForty premolars were allocated into four groups (n = 10 each): sound teeth and teeth with artificially induced WSLs, both subjected to at-home bleaching (16% carbamide peroxide) and in-office bleaching (35% hydrogen peroxide). WSLs were induced in half of the specimens using a 14-day pH-cycling protocol alternating between demineralizing and remineralizing solutions. HP permeability (µg/mL) and color parameters (L*, a*, b*, and WI
resultsWSLs subjected to in-office bleaching exhibited higher HP penetration compared to the other groups (p < 0.05). After bleaching, WSLs showed significantly lower L* and WI
conclusionsWhite spot lesions exhibited greater HP permeability and less favorable optical outcomes compared to sound teeth, particularly after in-office bleaching. CLINICAL RELEVANCE: Teeth with white spot lesions are more susceptible to HP diffusion and present less favorable whitening results. At-home bleaching may be a safer and more esthetically favorable conservative treatment option for managing white spot lesions.
Indexed as
Identifiers
40782153What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.