Evidence map›Paper›PMID 40782144›Full record

ArticleInternational forum of allergy & rhinology2025

Complications in Endoscopic Sinus Surgery: A TriNetX Network Analysis.

Jakob L Fischer, Tyler J Gallagher, Matthew E Lin, Ian Kim, Bozena B Wrobel, Daniel M Beswick, Jivianne T Lee, Marilene B Wang, Jeffrey D Suh

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International forum of allergy & rhinology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Complications in Endoscopic Sinus Surgery: A TriNetX Network Analysis.International forum of allergy & rhinology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jakob L FischerDepartment of Otolaryngology-Head and Neck Surgery, University of California, Los Angeles, California, USA.ORCID 0000-0002-8896-671X
Tyler J GallagherKeck School of Medicine of the University of Southern California, Los Angeles, California, USA.
Matthew E LinDepartment of Otolaryngology-Head and Neck Surgery, University of California, Los Angeles, California, USA.
Ian KimDepartment of Pediatrics and Department of Disease Prevention, Stanford University, Palo Alto, California, USA.
Bozena B WrobelDepartment of Otolaryngology-Head and Neck Surgery, University of Southern California, Los Angeles, California, USA.
Daniel M BeswickDepartment of Otolaryngology-Head and Neck Surgery, University of California, Los Angeles, California, USA.ORCID 0000-0001-8612-5442
Jivianne T LeeDepartment of Otolaryngology-Head and Neck Surgery, University of California, Los Angeles, California, USA.
Marilene B WangDepartment of Otolaryngology-Head and Neck Surgery, University of California, Los Angeles, California, USA.
Jeffrey D SuhDepartment of Otolaryngology-Head and Neck Surgery, University of California, Los Angeles, California, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe potential complications of endoscopic sinus surgery (ESS) remain a critical surgical consideration. This study aims to examine complication rates and identify trends in ESS-related complications.

methodsThe TriNetX network was queried for patients undergoing ESS between 2005 and 2024. Diagnosis and procedural codes identified patients with a new post-operative diagnosis relating to epistaxis, cerebrospinal fluid (CSF) leak, meningitis, and/or orbital injury. Complication rates were calculated. The relative risk for demographic differences in complication rates was assessed. Joinpoint regression analysis determined trends in complication rates.

resultsA total of 127,333 patients undergoing ESS were included. There was a 0.28% CSF leak rate, 0.24% meningitis rate, 2.09% rate of orbital complications, and 2.27% rate of hemorrhage requiring intervention. Among orbital complications, 0.10% of patients experienced retrobulbar hematoma, 0.40% experienced an extraocular muscle injury, and 0.30% experienced post-operative blindness or low vision. The 30-day readmission rates were 1.47% and 1.62% of patients sought emergency department (ED) care within 30 days of surgery. There were small but significant changes in rates of meningitis (annual percent change [APC] = ‒3.42; 95% confidence interval [CI] ‒5.65, 1.13), hemorrhage requiring intervention (APC = 3.0; 95% CI 1.92-4.10), and 30-day ED visits (APC = 5.43; 95% CI 2.52, 8.43) over time. There were multiple differences in complication rates based on patient sex, age, and race/ethnicity (p < 0.05)

conclusionsThere are age-related and demographic differences in complication rates related to ESS. The majority of complication rates have remained stable over 20 years, with only meningitis rates decreasing while rates of hemorrhage requiring intervention and emergency room visits have increased.

Indexed as

EndoscopyParanasal SinusesPostoperative ComplicationsAdolescentAdultAgedAged, 80 and overCerebrospinal Fluid LeakFemaleHumansMaleMeningitisMiddle AgedYoung Adultchronic rhinosinusitisendoscopic sinus surgerypost‐operativesinus surgery

Identifiers

PMID40782144
PMCPMC12676657

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.