Evidence map›Paper›PMID 40782139›Full record

Observational studyArchives of women's mental health2025

Expanding gender-sensitive and equitable substance use care models: treatment retention analysis of the women's drug dependent treatment program (PROMUD) replication in psychosocial units in Brazil.

Pedro Starzynski Bacchi, Fabio Carezzato, Talita di Santi, Paulo Suen, Felipe Silveira, Tiago Takeuchi, Joana Marczyk, Ricardo Trapé Trinca, Ronaldo Silva Torres, Silvia Brasiliano and 1 more

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in Archives of women's mental health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Observational
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Pedro Starzynski BacchiHospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (FMUSP), Instituto de Psiquiatria, São Paulo, Brazil. pedrobacchi@gmail.com.ORCID 0000-0002-5984-0608
Fabio CarezzatoHospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (FMUSP), Instituto de Psiquiatria, São Paulo, Brazil.
Talita di SantiHospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (FMUSP), Instituto de Psiquiatria, São Paulo, Brazil.
Paulo SuenHospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (FMUSP), Instituto de Psiquiatria, São Paulo, Brazil.
Felipe SilveiraHospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (FMUSP), Instituto de Psiquiatria, São Paulo, Brazil.
Tiago TakeuchiHospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (FMUSP), Instituto de Psiquiatria, São Paulo, Brazil.
Joana MarczykHospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (FMUSP), Instituto de Psiquiatria, São Paulo, Brazil.
Ricardo Trapé TrincaInstituto de Psicologia, Universidade de São Paulo, São Paulo, SP, Brazil.
Ronaldo Silva TorresInstituto de Psicologia, Universidade de São Paulo, São Paulo, SP, Brazil.
Silvia BrasilianoHospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (FMUSP), Instituto de Psiquiatria, São Paulo, Brazil.
Patricia HochgrafHospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (FMUSP), Instituto de Psiquiatria, São Paulo, Brazil.

Funding

Fundação de Amparo à Pesquisa do Estado de São Paulo 2003/06399-0
6 · The paper itself

Abstract

purposeThis study examines the challenges and opportunities of implementing gender-equitable substance use disorder (SUD) treatment models in Brazil by revisiting a public policy initiative carried out between 2004 and 2006. During this initiative, a structured model of care, the Women's Drug Dependent Treatment Program (PROMUD), was replicated in two additional psychosocial care units in São Paulo. The study seeks to contribute to the visibility of a historically hidden population of women with SUD by comparing treatment retention across the three centers and identifying risk factors associated with dropout.

methodThis observational, non-randomized post hoc analysis examined clinical data from 200 women who enrolled in PROMUD-based programs across three distinct psychosocial care centers-CAPS-AD Centro (DT), CAPS-AD Jardim Nélia (JN), and the original PROMUD site. All centers implemented the model concurrently using a standardized protocol. Treatment retention was defined as weeks between program admission and dropout (max follow-up: 104 weeks). Drop-out was defined as leaving treatment for reasons other than referral, improved discharge, administrative discharge, or death. Kaplan-Meier survival curves were used to estimate retention, and Cox proportional hazards models identified predictors of dropout.

results200 women were included, PROMUD had a higher percentage of white, educated and employed participants. DT had the highest prevalence of unstable housing and prostitution history. PROMUD and JN showed comparable retention at 104 weeks (44.8% and 42.4%), whereas DT exhibited the lowest retention (17.3%). Age was a protective factor (HR = 0.94, p < 0.001), substance of choice was not significantly associated with dropout.

conclusionGender-specific care models can be effectively implemented in resource-limited, community-responsive care units, though their success depends on local population characteristics and territorial dynamics. Despite the time gap since the original project, the challenges remain similar or have intensified.

Indexed as

Patient DropoutsSubstance Abuse Treatment CentersSubstance-Related DisordersAdultBrazilFemaleHumansMiddle AgedRisk FactorsBrazilGender-equitable carePROMUDPsychosocial careSubstance use disordersTreatment retentionWomen’s health

Identifiers

PMID40782139

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.