Evidence map›Paper›PMID 40782070›Full record

ReviewAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2025

Biodegradable Medical Implants: Reshaping Future Medical Practice.

Bo Xia, Yan Liu, Yangkun Xing, Zhewei Shi, Xiaocheng Pan

Abstract readReview
In one paragraph

Review in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
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  5. Article
  6. Review
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  10. Article
  11. Article
  12. Review
  13. Review
  14. Construction ofRegenerative biomaterials · 2026
    Article
  15. Review
  16. Article
  17. Review
  18. Biodegradable Medical Implants: Reshaping Future Medical Practice.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Bo XiaDepartment of Bioenvironment, Jiyang College of Zhejiang A&F University, Zhuji, 311800, China.ORCID https://orcid.org/0000-0002-7791-2636
Yan LiuDepartment of Bioenvironment, Jiyang College of Zhejiang A&F University, Zhuji, 311800, China.
Yangkun XingDepartment of Bioenvironment, Jiyang College of Zhejiang A&F University, Zhuji, 311800, China.
Zhewei ShiZhuji People's Hospital of Zhejiang Province, Zhuji, 311800, China.
Xiaocheng PanDepartment of Bioenvironment, Jiyang College of Zhejiang A&F University, Zhuji, 311800, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Biodegradable medical implants have fundamentally transformed the field of biomedical engineering by providing sustainable and biocompatible alternatives that obviate the need for secondary surgical removal and facilitate endogenous tissue regeneration. This comprehensive review systematically evaluates recent advancements in biodegradable implants utilized across a spectrum of medical applications, including internal medicine, surgical interventions, and medical devices. The developments discussed herein signify substantial progress in material synthesis, characterization, and processing techniques, effectively addressing critical challenges associated with the integration of biodegradable devices into medical implants. Although biodegradable medical implants promise advanced patient care, widespread clinical translation is hindered by inconsistent degradation rates mismatched with healing timelines, insufficient load-bearing strength, and potential inflammatory or toxic by-products. Additionally, most studies exhibit application-material imbalances, inadequate in vivo validation, and poorly controlled degradation behavior. Future efforts must clarify degradation mechanisms and treat materials as therapeutic agents. By synthesizing recent findings and highlighting critical gaps, this review provides valuable insights to guide innovation in biodegradable implant technologies, ultimately enhancing clinical outcomes and accelerating regenerative medicine's progress. Addressing these challenges is crucial for realizing their full clinical potential.

Indexed as

Absorbable ImplantsBiocompatible MaterialsBiomedical EngineeringProstheses and ImplantsRegenerative MedicineAnimalsHumansTissue EngineeringBiocompatible Materialsbiodegradable implantsbiodegradable materialsmedical implantssustainable biomedical engineering

Identifiers

PMID40782070
PMCPMC12462970

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.