Evidence map›Paper›PMID 40782064›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2025

Coordination Geometry Tuning in a Single-Atom Nanozyme to Mimic Metalloenzymes with Nonplanar Active Site.

Hyesung Lee, Changjoon Keum, Choah Kwon, Sangtae Kim, Youngdo Jeong, Sang-Yup Lee

Abstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hyesung LeeDepartment of Chemical and Biomolecular Engineering, Yonsei University, Seoul, 03722, Republic of Korea.ORCID https://orcid.org/0000-0003-0253-3110
Changjoon KeumCenter for Advanced Biomolecular Recognition, Biomedical Research Division, Korea Institute of Science and Technology (KIST), Seoul, 02792, Republic of Korea.
Choah KwonDepartment of Nuclear Engineering and Department of Materials Science and Engineering, Hanyang University, Seoul, 04763, Republic of Korea.
Sangtae KimDepartment of Nuclear Engineering and Department of Materials Science and Engineering, Hanyang University, Seoul, 04763, Republic of Korea.
Youngdo JeongCenter for Advanced Biomolecular Recognition, Biomedical Research Division, Korea Institute of Science and Technology (KIST), Seoul, 02792, Republic of Korea.
Sang-Yup LeeDepartment of Chemical and Biomolecular Engineering, Yonsei University, Seoul, 03722, Republic of Korea.ORCID https://orcid.org/0000-0003-1348-0296

Funding

Basic Science Research Program through National Research Foundation of Korea funded by Ministry of Science and ICT 2023R1A2C100438911KISTI Supercomputing Center KSC-2022-CRE-0457Korea Health Technology R&D Project through the Korea Health Industry Development Institute funded by Ministry of Health and Welfare HI19C075300National Research Foundation of Korea funded by Ministry of Science and ICT 2021M3D3A1A01079478
6 · The paper itself

Abstract

Single-atom nanozymes (SAzymes) have been developed to mimic metalloenzymes by modulating their coordination environment. However, the impact of the coordination geometry at the metal center on the catalytic activity of the SAzymes, particularly those with nonplanar active site configurations, has been minimally explored. Here, the effects of the geometric configuration of the Zn-N

Indexed as

Carbonic AnhydrasesMetalloproteinsNanostructuresZincCatalysisCatalytic DomainDensity Functional TheoryCarbonic AnhydrasesMetalloproteinsZinccarbonic anhydraseCO2coordination geometryhydrolysissingle‐atom nanozyme

Identifiers

PMID40782064
PMCPMC12442611

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.