Evidence map›Paper›PMID 40781874›Full record

ArticleInternational journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics2026

The impact of the COVID-19 pandemic on the diagnosis and management of pre-eclampsia: Identifying healthcare delays.

Juliana da-Costa-Santos, Vitor V L Reis, Rodolfo R Japecanga, Mariana Seabra, Maykon Anderson Carvalho, Ana Julia Ganzeli Oliveira, Laura Cintra Vinchi, Arthur B P Righi, Jussara Mayrink, José Paulo S Guida and 3 more

Abstract read
In one paragraph

Article in International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Validation of the fullPIERS model for predicting severe maternal outcomes in preeclampsia in five Brazilian centers.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026
    Article
  2. Review
  3. Direct versus referred admission to the maternity hospital due to preeclampsia: Does it influence pregnancy outcomes?International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026
    Article
  4. The impact of the COVID-19 pandemic on the diagnosis and management of pre-eclampsia: Identifying healthcare delays.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Juliana da-Costa-SantosDepartment of Obstetrics and Gynecology, School of Medical Sciences, Universidade Estadual de Campinas, Campinas, Brazil.ORCID https://orcid.org/0000-0002-2708-350X
Vitor V L ReisDepartment of Obstetrics and Gynecology, School of Medical Sciences, Universidade Estadual de Campinas, Campinas, Brazil.
Rodolfo R JapecangaDepartment of Obstetrics and Gynecology, School of Medical Sciences, Universidade Estadual de Campinas, Campinas, Brazil.
Mariana SeabraDepartment of Obstetrics and Gynecology, School of Medical Sciences, Universidade Estadual de Campinas, Campinas, Brazil.
Maykon Anderson CarvalhoDepartment of Obstetrics and Gynecology, School of Medical Sciences, Universidade Estadual de Campinas, Campinas, Brazil.
Ana Julia Ganzeli OliveiraDepartment of Obstetrics and Gynecology, School of Medical Sciences, Universidade Estadual de Campinas, Campinas, Brazil.
Laura Cintra VinchiDepartment of Obstetrics and Gynecology, School of Medical Sciences, Universidade Estadual de Campinas, Campinas, Brazil.
Arthur B P RighiPontifical Catholic University of Campinas, Brazil.
Jussara MayrinkDepartment of Obstetrics and Gynecology, School of Medicine, Federal University of Minas Gerais, Belo Horizonte, Brazil.
José Paulo S GuidaDepartment of Obstetrics and Gynecology, School of Medical Sciences, Universidade Estadual de Campinas, Campinas, Brazil.
Renato T SouzaDepartment of Obstetrics and Gynecology, School of Medical Sciences, Universidade Estadual de Campinas, Campinas, Brazil.
José G CecattiDepartment of Obstetrics and Gynecology, School of Medical Sciences, Universidade Estadual de Campinas, Campinas, Brazil.
Maria Laura CostaDepartment of Obstetrics and Gynecology, School of Medical Sciences, Universidade Estadual de Campinas, Campinas, Brazil.ORCID https://orcid.org/0000-0001-8280-3234

Funding

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior 88887.896655/2023-00Faculdade de Ciências Médicas, Universidade Estadual de CampinasFundação de Amparo à Pesquisa do Estado de São Paulo 408407/2021-2
6 · The paper itself

Abstract

objectiveTo compare the prevalence of pre-eclampsia with and without severe features, and maternal and perinatal outcomes before and during the COVID-19 pandemic.

methodsCross-sectional study based on medical chart review of pregnant women admitted to a referral maternity hospital for childbirth between September 2019 to February 2020 (before the pandemic) and March 2020 to August 2021 (during the pandemic, subdivided into three 6-month periods). The prevalence of pre-eclampsia, maternal, and perinatal outcomes were compared.

resultsA total of 3914 deliveries were considered, 1059 pre-pandemic and 2855 during the pandemic. The overall prevalence of pre-eclampsia was 10.9%, not differing significantly among periods (9.3%-14.3%, P = 0.144). Social and demographic characteristics were similar between groups. The use of anti-hypertensive therapy during pregnancy decreased significantly (69.9% pre-pandemic versus 47.1%-54.0% during the pandemic, P = 0.007). The diagnosis of early-onset pre-eclampsia reduced significantly (37.9% before and 19.3%-30.2% during the pandemic, P = 0.025), and so did the proportion of severe pre-eclampsia (61.1% before and 38.1%-58.3% during the pandemic, P = 0.001). However, the gestational age at birth was similar between groups, around 36 weeks. COVID-19 positivity increased from 0.9% to 12.0% during the pandemic periods (P < 0.001). There were no maternal deaths. Newborns were less often admitted to intensive care during the pandemic, and over 60% of these admissions were the result of prematurity in all periods studied. Other perinatal outcomes remained similar.

conclusionThe prevalence of pre-eclampsia increased during the study period, with diagnoses occurring at later gestational ages, likely due to delays in healthcare access.

Indexed as

COVID-19Delayed DiagnosisPre-EclampsiaTime-to-TreatmentAdultCross-Sectional StudiesFemaleHumansInfant, NewbornPregnancyPregnancy OutcomePrevalenceSARS-CoV-2Young AdultCOVID‐19pandemic preparednesspre‐eclampsiapregnancy complicationspublic health surveillance

Identifiers

PMID40781874
PMCPMC12790658

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.