Evidence map›Paper›PMID 40781785›Full record

ArticleJournal of neurochemistry2025

Phosphoinositide- and Collybistin-Dependent Synaptic Clustering of Gephyrin.

Nele Burdina, Filip Liebsch, Arthur Macha, Joaquín Lucas Ortuño Gil, Pia Frommelt, Irina Rais, Fabian Basler, Simon Pöpsel, Guenter Schwarz

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of neurochemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. GABACellular and molecular neurobiology · 2026
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Nele BurdinaDepartment of Chemistry and Biochemistry, Institute of Biochemistry, University of Cologne, Cologne, Germany.ORCID https://orcid.org/0009-0000-3200-918X
Filip LiebschDepartment of Chemistry and Biochemistry, Institute of Biochemistry, University of Cologne, Cologne, Germany.ORCID https://orcid.org/0000-0002-0955-8065
Arthur MachaDepartment of Chemistry and Biochemistry, Institute of Biochemistry, University of Cologne, Cologne, Germany.ORCID https://orcid.org/0009-0007-1798-4412
Joaquín Lucas Ortuño GilDepartment of Chemistry and Biochemistry, Institute of Biochemistry, University of Cologne, Cologne, Germany.
Pia FrommeltDepartment of Chemistry and Biochemistry, Institute of Biochemistry, University of Cologne, Cologne, Germany.
Irina RaisDepartment of Chemistry and Biochemistry, Institute of Biochemistry, University of Cologne, Cologne, Germany.ORCID https://orcid.org/0000-0002-0367-1980
Fabian BaslerCenter for Molecular Medicine Cologne (CMMC), Faculty of Medicine and University Hospital, University of Cologne, Cologne, Germany.ORCID https://orcid.org/0000-0001-8999-2568
Simon PöpselCenter for Molecular Medicine Cologne (CMMC), Faculty of Medicine and University Hospital, University of Cologne, Cologne, Germany.ORCID https://orcid.org/0000-0002-8304-4062
Guenter SchwarzDepartment of Chemistry and Biochemistry, Institute of Biochemistry, University of Cologne, Cologne, Germany.ORCID https://orcid.org/0000-0002-2118-9338

Funding

CANTAR network funded by the Ministry of Culture and Science of the state of Northrine-WestphaliaCenter for Molecular Medicine Cologne, University of Cologne JRGXIDeutsche Forschungsgemeinschaft 411422114Deutsche Forschungsgemeinschaft 424228829Deutsche Forschungsgemeinschaft 504090354
6 · The paper itself

Abstract

Gephyrin is the main scaffolding protein at inhibitory synapses, clustering glycine and GABA

Indexed as

Carrier ProteinsMembrane ProteinsPhosphatidylinositolsRho Guanine Nucleotide Exchange FactorsSynapsesAnimalsHumansMicePhosphorylationRatsCarrier ProteinsgephyrinMembrane ProteinsPhosphatidylinositolsRho Guanine Nucleotide Exchange FactorscollybistinGABA receptorsgephyrininhibitory synapsephosphoinositidessynaptic clustering

Identifiers

PMID40781785
PMCPMC12334862

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.