SynthesisJournal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG2025
Treatment of Xanthoma disseminatum - a systematic literature review.
Synthesis in Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed, 1 synthesis or guideline pooled it.
- Treatment of Xanthoma disseminatum - a systematic literature review.Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG · 2025Pooled it
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Xanthoma disseminatum is a rare disease from the spectrum of non-Langerhans cell histiocytoses, which can be categorized into three types and is sometimes associated with systemic involvement. Due to the its rarity, there are no standardized treatment guidelines for this disease, making treatment in everyday clinical practice more difficult. The aim of this study was therefore to summarize the therapeutic experience of the last 22 years by conducting a systematic literature review and thus generate an overview of the various treatment options. A systematic literature review on the topic of xanthoma disseminatum and applied treatment strategies was conducted in the PubMed/MEDLINE database for the period from 26 June 2002 to 26 June 2024. The literature search resulted in 38 publications, 19 of which were included in the review. The therapeutic approaches of the studies analyzed can be divided into immunosuppressive, cytostatic-based, lipid-lowering, surgical, UV radiation, and laser-based therapeutic approaches. Therapy with cladribine was reported most frequently. The current data is mainly based on case reports and case series, which are presented and summarized in this review. It can therefore be used as a basis for treatment decisions.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.