Evidence map›Paper›PMID 40781710›Full record

ArticleBMC pulmonary medicine2025

Technical evaluation of Turbuhaler

Lina Liang, Ruogang Huang, Yun Li, Zhufeng Wang, Kang Peng, Junfeng Lin, Feifei Huang, Xiaoyin Yao, Jinping Zheng, Yi Gao

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC pulmonary medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Lina Liang *National Clinical Research Center for Respiratory Disease, National Center for Respiratory Medicine, State Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital, Guangzhou Medical University, Guangzhou, Guangdong, China.
Ruogang Huang *Guangzhou Nansha Maternity & Child Healthcare Hospital, Guangzhou, China.
Yun Li *National Clinical Research Center for Respiratory Disease, National Center for Respiratory Medicine, State Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital, Guangzhou Medical University, Guangzhou, Guangdong, China.
Zhufeng Wang *National Clinical Research Center for Respiratory Disease, National Center for Respiratory Medicine, State Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital, Guangzhou Medical University, Guangzhou, Guangdong, China.
Kang PengNational Clinical Research Center for Respiratory Disease, National Center for Respiratory Medicine, State Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital, Guangzhou Medical University, Guangzhou, Guangdong, China.
Junfeng LinNational Clinical Research Center for Respiratory Disease, National Center for Respiratory Medicine, State Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital, Guangzhou Medical University, Guangzhou, Guangdong, China.
Feifei HuangNational Clinical Research Center for Respiratory Disease, National Center for Respiratory Medicine, State Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital, Guangzhou Medical University, Guangzhou, Guangdong, China.
Xiaoyin YaoNational Clinical Research Center for Respiratory Disease, National Center for Respiratory Medicine, State Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital, Guangzhou Medical University, Guangzhou, Guangdong, China.
Jinping ZhengNational Clinical Research Center for Respiratory Disease, National Center for Respiratory Medicine, State Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital, Guangzhou Medical University, Guangzhou, Guangdong, China. jpzhenggy@163.com.
Yi GaoNational Clinical Research Center for Respiratory Disease, National Center for Respiratory Medicine, State Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital, Guangzhou Medical University, Guangzhou, Guangdong, China. misstall2@163.com.

Funding

Noncommunicable Chronic Diseases-National Science and Technology Major Project 2023ZD0506300
6 · The paper itself

Abstract

backgroundThe Turbuhaler

methodsThis study recruited asthmatic children aged 4 to 14 years who were using the Turbuhaler

resultsOf the 141 enrolled patients, 50 (35.5%) scored 10 points on the checklist. Overall, 105 (74.4%), 28 (19.9%) and 8 (5.7%) patients performed good, moderate, and poor inhaler technique, respectively. The three common improper steps were ''exhale to residual volume'' (35.5%), "inhale forcefully and deeply" (13.5%), "rinse mouth after inhalation" (13.5%). The three common inappropriate inhalation parameters were "Effective inspiratory time(EIT) < 2s" (90.8%), "Peak inspiratory flow rate(PIFR) < 60L/min" (41.8%), and "Breath-hold time(BHT) < 5s" (27.0%). In the three groups with good, moderate, poor inhaler techniques, 0, 2 (7.1%), and 2 (25.0%) patients did not reach the minimum PIFR. Meanwhile, 38 (36.2%), 15 (53.6%), and 6 (75.0%) patients did not reach the optimal PIFR, respectively. The results of ordered logistic regression analysis indicated that low medication adherence (P = 0.045), PIFR (P = 0.041), BHT (P = 0.003) and the duration of Turbuhaler

conclusionThe improper use of inhalers and inappropriate inhalation parameters are common among asthmatic children. Using checklist and inhalation parameters enables a more comprehensive evaluation of the patients' inhalation maneuvers and inspiratory effort.

trial registrationThis study is registered at Chictr.org with the identifier number ChiCTR2200056579.

Indexed as

AsthmaDry Powder InhalersAdministration, InhalationAdolescentChecklistChildChild, PreschoolFemaleHumansMaleBronchial asthmaChildrenInhalation parametersInhaler techniqueTurbuhaler®

Identifiers

PMID40781710
PMCPMC12333242

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.