ArticleBMC public health2025
Association between estimated glucose disposal rate and heart failure in patients with diabetes or prediabetes: a cross-sectional study.
Article in BMC public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo examine the association between estimated glucose disposal rate (eGDR) and the prevalence of self-reported heart failure among patients with diabetes or prediabetes from the National Health and Nutrition Examination Survey (NHANES).
methodsThis cross-sectional study selected data from eight cycles (one every two years) of the NHANES study from 2003 to 2018 and included 9,017 participants. Tertiles of calculated eGDR initially grouped patients with diabetes and prediabetes. Weighted multivariate logistic regression models were then utilized to investigate the correlation between varying levels of eGDR and the prevalence of self-reported heart failure. Subsequently, smoothed fit curves were employed to assess a potential association between cumulative eGDR and the prevalence of self-reported heart failure. Finally, subgroup analyses were conducted.
resultsIn the final analysis of all 9,017 participants who met the study requirements in the fully covariate-adjusted model, eGDR was found to be linearly and negatively associated with the incidence of heart failure among US patients with diabetes or prediabetes (P non-linear = 0.5424). Furthermore, in the fully covariate-adjusted continuous model, each 1-unit increase in eGDR was associated with a 23% reduction in the risk of heart failure (odds ratio [OR]: 0.77, 95% confidence interval [CI]: 0.69-0.85, p < 0.0001). In the fully covariate-adjusted categorical model, participants in the highest tertile (Q3) exhibited a 69% lower risk of developing heart failure compared to those in the lowest tertile (Q1) (OR: 0.31, 95% CI: 0.17-0.57, p < 0.001). Subgroup analyses revealed the potential for an interaction in ethnic subgroups.
conclusionThe present study established a significant negative correlation between the eGDR levels and the incidence of heart failure in US patients with diabetes or prediabetes. This suggests that eGDR may have a potential role in associated with the prevalence of heart failure in the overall population. It is also noteworthy that eGDR is associated with the onset of several diseases.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.