Evidence map›Paper›PMID 40781671›Full record

ArticleBMC health services research2025

Using a digital health platform to implement a multi-component CRC screening intervention within a federally qualified health center: study protocol for a hybrid type I trial.

Leah Frerichs, Zhang Zhang, Alexis A Moore, Isabelle Falk, Xianming Tan, Aliza Randazzo, Alison T Brenner, Daniel S Reuland, Ajay Dharod, David P Miller

Registry-linked trialAbstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC health services research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06441487 (Evaluating a Remotely Delivered, Digital Health CRC Screening Intervention Among Racially Diverse Patients of a Community Health Center), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06441487 naactive not recruitingnot on this map

Evaluating a Remotely Delivered, Digital Health CRC Screening Intervention Among Racially Diverse Patients of a Community Health Center

TypeinterventionalSponsorUNC Lineberger Comprehensive Cancer CenterRan2025 to 2029Enrolled1,062ConditionsColorectal CancerArmsMobile Health Decision Support, Usual care
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Leah FrerichsDepartment of Health Policy and Management, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. leahf@unc.edu.
Zhang ZhangDepartment of Health Policy and Management, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Alexis A MooreLineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Isabelle FalkLineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Xianming TanLineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Aliza RandazzoDepartment of Implementation Science, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
Alison T BrennerLineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Daniel S ReulandLineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Ajay DharodDepartment of Implementation Science, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
David P MillerDepartment of Implementation Science, Wake Forest University School of Medicine, Winston-Salem, NC, USA.

Funding

North Carolina Translational and Clinical Sciences Institute (NC TraCS)UM1TR004406 · NCATS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI NICHOLAS J SHAHEEN · 2023 to 2026
$37.5M
Evaluating a remotely delivered, digital health CRC screening intervention among rural patients of a community health center R01CA273331 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Leah M. Frerichs · 2023 to 2026
$2.4M
NCATS NIH HHS UM1 TR004406NCATS NIH HHS UM1TR004406NCI NIH HHS R01 CA273331NCI NIH HHS R01CA273331
6 · The paper itself

Abstract

backgroundOver the past decade, many well-resourced health plans and systems surpassed the 80% colorectal cancer screening rate goal, while lower resource environments such as federally qualified health centers (FQHCs) lag behind. FQHCs in rural areas are especially challenged with limited resources to reach diverse patients who often lack consistent engagement with clinical care. mHealth solutions, like mPATH

methodsFollowing a type 1 hybrid effectiveness-implementation design, we will conduct a patient-level randomized controlled trial (RCT) to assess the effectiveness of mPATH DISCUSSION: This trial will generate insights into the effectiveness and implementation of a digital CRC screening intervention in resource-limited FQHCs. Findings will inform strategies for optimizing outreach components and scaling implementation in similar settings.

trial registrationThis trial was registered on June 4, 2024, at ClinicalTrials.gov (identifier NCT06441487).

Indexed as

Colorectal NeoplasmsEarly Detection of CancerMass ScreeningSafety-net ProvidersTelemedicineDigital HealthHumansRandomized Controlled Trials as TopicColorectal cancer screeningDigital health technologiesImplementation science

Identifiers

PMID40781671
PMCPMC12335168

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.