Evidence map›Paper›PMID 40781616›Full record

Trial reportBMC oral health2025

The effect of Polyvinylpyrrolidone-Sodium hyaluronate gel on palatal wound healing: a randomized controlled clinical trial.

Tugba Bulut, Nuray Ercan

Registry-linked trialAbstract readRandomized Controlled TrialComparative Study
In one paragraph

Trial report in BMC oral health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06610331 (EVALUATION OF THE EFFECT OF POLYVINYLPYROLIDONE AND SODIUM HYALURONATE GEL ON PALATINAL WOUND HEALING), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06610331 nacompletednot on this map

Evaluation of the effect of polyvinylpyrolidone and sodium hyaluronate gel on palatinal wound healing: a randomized controlled clinical study

TypeinterventionalSponsorAbant Izzet Baysal UniversityRan2024 to 2024Enrolled32ConditionsPalatal WoundArmsFREE GİNGİVAL GRAFT, polyvinylpyrrolidone sodium hyaluronate gel
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Tugba BulutDepartment of Periodontology, Faculty of Dentistry, Bolu Abant Izzet Baysal University, Bolu, Turkey.
Nuray ErcanDepartment of Periodontology, Faculty of Dentistry, Bolu Abant Izzet Baysal University, Bolu, Turkey. nryerc@hotmail.com.

Funding

Bolu Abant Izzet Baysal University Scientific Research Center 2023-TUP-6.12.47-0005
6 · The paper itself

Abstract

backgroundThis study evaluates the effect of polyvinylpyrrolidone sodium hyaluronate gel (Gelclair

methodsThirty-two patients undergoing FGG were randomly assigned to two groups: the test group received Gelclair

resultsH₂O₂ test values significantly decreased and WHI values significantly increased over time in both groups (p < 0.050). Test and control groups comparison at time points showed the test group showed significantly lower H₂O₂ test values on days 7, 14, and 28 (p < 0.050) and higher WHI values on days 3, 7, 14, and 28 compared to control group. VAS pain, chewing, and burning scores were also significantly lower in the test group on days 1, 3, 7, and 14 compared to control. While on day 1, the control group had a bleeding rate of 105 times higher than the test group (p < 0.001), no significant differences were observed on days 3 and 7.

conclusionsThe findings suggest that Gelclair TRIAL REGISTRATION NUMBER: NCT06610331; Retrospectively registered on 23/09/2024.

Indexed as

GingivaHyaluronic AcidPalatePovidoneWound HealingAdultAnti-Infective Agents, LocalChlorhexidineFemaleFollow-Up StudiesGelsHumansHydrogen PeroxideMaleMiddle AgedMouthwashesAnti-Infective Agents, LocalChlorhexidineGelsHyaluronic AcidHydrogen PeroxideMouthwashesPovidoneDonor siteFree gingival graftHyaluronic acidPainPostoperative complicationsWound healing

Identifiers

PMID40781616
PMCPMC12333267

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.