Evidence map›Paper›PMID 40781500›Full record

ArticleCommunications biology2025

Resynchronization of microglial activity in the brain is associated with restoration of motor function in Parkinson's disease.

Peizhen Ye, Lei Bi, Yifan Qiu, Min Yang, Yongshan Liu, Yuyi Hou, Pengcheng Zheng, Xiaojuan Cao, Jing Su, Hongjun Jin

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Communications biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Peizhen YeGuangdong Provincial Engineering Research Center of Molecular Imaging, The Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai City, Guangdong Province, 519000, China.
Lei BiGuangdong Provincial Engineering Research Center of Molecular Imaging, The Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai City, Guangdong Province, 519000, China.
Yifan QiuGuangdong Provincial Engineering Research Center of Molecular Imaging, The Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai City, Guangdong Province, 519000, China.
Min YangGuangdong Provincial Engineering Research Center of Molecular Imaging, The Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai City, Guangdong Province, 519000, China.
Yongshan LiuGuangdong Provincial Engineering Research Center of Molecular Imaging, The Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai City, Guangdong Province, 519000, China.
Yuyi HouGuangdong Provincial Engineering Research Center of Molecular Imaging, The Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai City, Guangdong Province, 519000, China.
Pengcheng ZhengGuangdong Provincial Engineering Research Center of Molecular Imaging, The Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai City, Guangdong Province, 519000, China.
Xiaojuan CaoDepartment of Hematology, Washington University School of Medicine, St. Louis, MO, 63110, USA.
Jing SuSchool of Chinese Medicine, The University of Hong Kong, Pokfulam, Hong Kong.
Hongjun JinGuangdong Provincial Engineering Research Center of Molecular Imaging, The Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai City, Guangdong Province, 519000, China. jinhj3@mail.sysu.edu.cn.ORCID http://orcid.org/0000-0002-1522-1098

Funding

National Natural Science Foundation of China (National Science Foundation of China) 82372004,81871382, 82150610508
6 · The paper itself

Abstract

Neuroinflammation is a key factor in Parkinson's disease (PD) pathogenesis. However, the regional heterogeneity of biomarkers related to inflammation in PD is less well defined. We developed [

Indexed as

BrainMicrogliaMotor ActivityParkinson DiseaseAcetatesAnimalsCyclopropanesDisease Models, AnimalMaleMiceMice, Inbred C57BLPositron-Emission TomographyQuinolinesReceptors, Purinergic P2X7SulfidesAcetatesCyclopropanesQuinolinesReceptors, Purinergic P2X7Sulfides

Identifiers

PMID40781500
PMCPMC12334669

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.