ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2025
Clinical trial-related financial considerations from Deep South-patients with breast cancer who previously declined trial participation.
Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThis study explored perspectives on clinical trial-related financial considerations from patients with breast cancer receiving treatment in the Deep South who declined trial participation.
methodsThis qualitative content analysis included interview data from patients offered participation in a breast cancer clinical trial yet declined to participate from July 2020 to January 2024. Semi-structured interviews elucidated the influence of financial factors in the decision to decline enrollment onto a trial. Open coding was used to develop the codebook via an inductive approach to identify key concepts, patterns, and themes from the transcribed interviews. Transcribed interviews were then coded deductively by two independent reviewers.
resultsOf 21 patients with breast cancer, 43% and 57% previously declined participation in a therapeutic and non-therapeutic clinical trial. Interviews revealed four themes related to the influence of financial factors in the decision to decline participation in clinical trials, including (1) trial participation expenses (e.g., direct and indirect participation expenses), (2) insurance coverage (e.g., barriers for insured, resource for uninsured), (3) socioeconomic status (inequities and trust in clinical trials), and (4) financial compensation for trial participation (e.g., facilitating participation, inappropriate incentivizing).
conclusionFuture interventions targeting financial barriers to trial participation for patients most vulnerable to experiencing financial disparities are needed to diversify cancer clinical trial participation, thus ensuring results are generalizable to all patients.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.