Evidence map›Paper›PMID 40781387›Full record

SynthesisAnnals of surgical oncology2025

Feasibility and Efficacy of Decision Aids to Improve Decision-Making for Contralateral Prophylactic Mastectomy: A Systematic Review.

Ariana Naaseh, Sophia X Tang, Kim L Lipsey, Mary C Politi, Julie A Margenthaler

Abstract readSystematic Review
In one paragraph

Synthesis in Annals of surgical oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ariana NaasehDivision of Surgical Oncology, Department of Surgery, Washington University School of Medicine, St. Louis, MO, USA.
Sophia X TangDivision of Surgical Oncology, Department of Surgery, Washington University School of Medicine, St. Louis, MO, USA.
Kim L LipseyBecker Medical Library, Washington University School of Medicine, St. Louis, MO, USA.
Mary C PolitiSchool of Public Health, Washington University in St. Louis, St. Louis, MO, USA.
Julie A MargenthalerDivision of Surgical Oncology, Department of Surgery, Washington University School of Medicine, St. Louis, MO, USA. jmargenthaler@wustl.edu.

Funding

SURGICAL ONCOLOGY TRAINING GRANTT32CA009621 · NCI · WASHINGTON UNIVERSITY · PI TIMOTHY J. EBERLEIN, William E. Gillanders · 1988 to 2026
$12.9M
NCI NIH HHS T32 CA009621NCI NIH HHS T32CA009621
6 · The paper itself

Abstract

backgroundRates of contralateral prophylactic mastectomy (CPM) for unilateral breast cancer have increased significantly. Decision aids (DAs) can support the shared decision-making process. This study systematically reviewed the literature to understand the feasibility and efficacy of using DAs to improve decision outcomes about CPM.

methodsSix databases were searched through April 2024. Included studies reported on patient DAs about CPM after diagnosis of unilateral breast cancer for average- or low-risk patients. Two investigators reviewed 6186 abstracts and 155 full-text articles, extracting data for studies that met the criteria. Data quality assessment was performed using GRADE.

resultsThe review included six studies published from 2017 to 2021. Four (66.7%) studies reported solely on patient acceptance of the DAs, whereas two (33.3%) studies included clinicians. Three (50%) DAs were formatted for online delivery, whereas two (33.3%) were formatted for paper delivery, and one (16.7%) was formatted for unknown delivery. Two (33.3%) research teams used a multi-disciplinary group to develop their DA. Overall, patient satisfaction with the DAs was high, and knowledge scores increased, but little consensus existed on when to introduce the DA. Important DA characteristics measured were use with or without a clinician, literacy considerations, and the order and balance of information.

conclusionsMore research should be conducted to develop and test DAs for CPM decisions, with attention to the balance of information, type of content, format, timing, and optimal delivery of such DAs. Future research in larger, multi-institutional populations using standardized, validated measures for satisfaction, values, decisional conflict, and health literacy could assess the impact of DAs for CPM.

Indexed as

Breast NeoplasmsDecision MakingDecision Making, SharedDecision Support TechniquesPatient ParticipationProphylactic MastectomyFeasibility StudiesFemaleHumansPrognosisBreast cancerBreast surgeryContralateral prophylactic mastectomyDecision aidsDecisionsShared decision-making

Identifiers

PMID40781387
PMCPMC12711632

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.