Evidence map›Paper›PMID 40781116›Full record

ArticleScientific reports2025

Accelerated wound healing through tannin-rich Jaft extract, concentration-dependent efficacy and mechanistic insights from Quercus brantii ointment formulations.

Seyedeh Sabereh Samavati, Soheila Kashanian, Hossein Derakhshankhah, Morteza Rabiei, Soraya Sajadimajd, Sajad Fakhri, Zahra Rashidi

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Seyedeh Sabereh SamavatiDepartment of Nanobiotechnology, Razi University, P.O. Box 67149, Kermanshah, Iran.
Soheila KashanianDepartment of Nanobiotechnology, Razi University, P.O. Box 67149, Kermanshah, Iran. kashanian_s@yahoo.com.
Hossein DerakhshankhahPharmaceutical Sciences Research Center, Health Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Morteza RabieiDepartment of Nanobiotechnology, Razi University, P.O. Box 67149, Kermanshah, Iran. mrabiei6768@gmail.com.
Soraya SajadimajdDepartment of Biology, Faculty of Science, Razi University, Kermanshah, Iran.
Sajad FakhriMedical Biology Research Center, Health Technology Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Zahra RashidiFertility and Infertility Research Center, Health Technology Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran.

Funding

Iran National Science Foundation 99027375
6 · The paper itself

Abstract

Jaft extract exhibits anti-inflammatory, antimicrobial, antioxidant, and astringent properties, making it a promising therapeutic agent for wound treatment. This study aims to synthesize an the ointment containing varying concentrations of Jaft extract and evaluate its efficacy in promoting wound healing. By understanding that prompt wound washing prevents infection and acts as an astringent, we observe its dual role in achieving hemostasis and controlling bleeding. The second aim is to assess the impact of early wound cleansing with Jaft extract on treatment outcomes. A comparative study was conducted to evaluate the impact of preliminary wound washing with Jaft extract before ointment application on healing efficacy. Three ointment formulations (2%, 4%, and 8% w/w Jaft extract) were prepared. Wound healing parameters in rats included wound closure rate, levels of catalase and glutathione antioxidants, histopathological analysis, hydroxyproline content, and tissue-breaking strength. The Jaft extract exhibited potent antioxidant (3.72 μg/mL) and anti-inflammatory (IC

Indexed as

Plant ExtractsQuercusTanninsWound HealingAnimalsAnti-Inflammatory AgentsAntioxidantsMaleOintmentsRatsRats, WistarSkinAnti-Inflammatory AgentsAntioxidantsOintmentsPlant ExtractsTanninsAstringentHomeostasisJaftOintmentTanninWound healing

Identifiers

PMID40781116
PMCPMC12334769

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.