Evidence map›Paper›PMID 40780992›Full record

ArticleTrends in genetics : TIG2025

Unraveling immunity: insights from biobank-scale data.

Ashley Richardson, Kailash Bp, Chad H Hogan

Abstract readEditorial
In one paragraph

Article in Trends in genetics : TIG, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ashley RichardsonInstitute for Genomic Health, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Genomics Preprint Club, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Kailash BpGenomics Preprint Club, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Nash Family Department of Neuroscience and Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Ronald M. Loeb Center for Alzheimer's Disease, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Chad H HoganInstitute for Genomic Health, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Genomics Preprint Club, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA. Electronic address: chad.hogan@mssm.edu.

Funding

TRAINING PROGRAM IN CANCER THERAPYT32CA078207 · NCI · MOUNT SINAI SCHOOL OF MEDICINE OF NYU · PI James J Manfredi · 1999 to 2026
$11.6M
Learning the Regulatory Code of Alzheimer's Disease GenomesU01AG068880 · NIA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI KNOWLES, DAVID ARTHUR, RAJ, TOWFIQUE · 2020 to 2024
$5.8M
Modeling the impact of regulatory and splicing variants on cellular function in Alzheimer's diseaseRF1AG065926 · NIA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI BRENNAND, KRISTEN JENNIFER, RAJ, TOWFIQUE · 2021 to 2021
$2.4M
Identifying genetic and sociodemographic determinants of susceptibility to infectious diseases in diverse population groupsR21MD019104 · NIMHD · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI ASGARI, SAMIRA · 2023 to 2024
$444k
NCI NIH HHS T32 CA078207NIA NIH HHS RF1 AG065926NIA NIH HHS U01 AG068880NIMHD NIH HHS R21 MD019104
6 · The paper itself

Abstract

The scale and granularity of biobanks are reshaping the future of immunogenetics, enabling breakthroughs at a pace never before possible. Here, we highlight two recent preprints that apply novel statistical methods to biobank data to understand how inherited variants shape immune traits and disease risk.

Indexed as

Biological Specimen BanksImmunityGenetic Predisposition to DiseaseHumansImmunogenetics

Identifiers

PMID40780992
PMCPMC12478156

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.