Evidence map›Paper›PMID 40780873›Full record

Observational studyCanadian journal of surgery. Journal canadien de chirurgie

Matching males and females undergoing Shouldice repair using a prospective, longitudinal design.

Marguerite Mainprize, Anton Svendrovski, Christoph Paasch, Ayse Yilbas, Joel Katz

Registry-linked trialAbstract readObservational Study
In one paragraph

Observational study in Canadian journal of surgery. Journal canadien de chirurgie. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03986060 (Shouldice Hospital Outcome Study), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03986060 unknown statusnot on this map

Shouldice Hospital Outcome Study

TypeobservationalSponsorYork UniversityRan2019 to 2024Enrolled3,000ConditionsInguinal Hernia
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Marguerite MainprizeFrom the Department of Surgery, Shouldice Hospital, Ont. (Mainprize, Paasch, Yilbas); the Department of General Surgery, University Hospital Brandenburg an der Havel, Brandenburg Medical School Theodor Fontane, Brandenburg, Germany (Mainprize, Paasch); UZIK Consulting Inc. Toronto, Ont. (Svendrovski); the Department of Psychology, York University, Ont. (Katz) mmainprize@shouldice.com.
Anton SvendrovskiFrom the Department of Surgery, Shouldice Hospital, Ont. (Mainprize, Paasch, Yilbas); the Department of General Surgery, University Hospital Brandenburg an der Havel, Brandenburg Medical School Theodor Fontane, Brandenburg, Germany (Mainprize, Paasch); UZIK Consulting Inc. Toronto, Ont. (Svendrovski); the Department of Psychology, York University, Ont. (Katz).
Christoph PaaschFrom the Department of Surgery, Shouldice Hospital, Ont. (Mainprize, Paasch, Yilbas); the Department of General Surgery, University Hospital Brandenburg an der Havel, Brandenburg Medical School Theodor Fontane, Brandenburg, Germany (Mainprize, Paasch); UZIK Consulting Inc. Toronto, Ont. (Svendrovski); the Department of Psychology, York University, Ont. (Katz).
Ayse YilbasFrom the Department of Surgery, Shouldice Hospital, Ont. (Mainprize, Paasch, Yilbas); the Department of General Surgery, University Hospital Brandenburg an der Havel, Brandenburg Medical School Theodor Fontane, Brandenburg, Germany (Mainprize, Paasch); UZIK Consulting Inc. Toronto, Ont. (Svendrovski); the Department of Psychology, York University, Ont. (Katz).
Joel KatzFrom the Department of Surgery, Shouldice Hospital, Ont. (Mainprize, Paasch, Yilbas); the Department of General Surgery, University Hospital Brandenburg an der Havel, Brandenburg Medical School Theodor Fontane, Brandenburg, Germany (Mainprize, Paasch); UZIK Consulting Inc. Toronto, Ont. (Svendrovski); the Department of Psychology, York University, Ont. (Katz).

Funding

CIHR
6 · The paper itself

Abstract

backgroundSex differences in chronic postsurgical pain have been reported, with the main findings indicating that females experience a greater incidence and severity of pain than males; however, it remains unclear to what these sex differences are attributable. We sought to compare pain and related psychological factors between a matched sample of male and female patients 3 months and 1 year after Shouldice repair.

methodsMale and female participants who underwent Shouldice repair were manually matched 1:1 and compared on 10 variables: age, body mass index, smoking status, preoperative depression and anxiety scores, living status (alone or with others), American Society of Anesthesiologists physical status health classification, preoperative chronic pain, preoperative hernia pain, preoperative pain catastrophizing scores, and nerve handling during surgery. Data on pain were collected from questionnaires administered 3 months and 1 year postoperatively, and data on participant clinical characteristics were collected from operative notes and patient charts.

resultsThere were 28 matched male-female pairs at 3 months and 21 at 1 year. The average age preoperatively was 56.18 ± 12.48 years. At 3 months postoperative, 18 females and 6 males had pain (

conclusionAfter matching on important confounders, sex differences were found in pain frequency, duration, incidence, and severity at 3 months after Shouldice repair. However, by 1 year after surgery the differences were no longer significant.

trial registrationClinicaltrials.gov # NCT03986060.

Indexed as

Chronic PainHerniorrhaphyPostoperative PainAdultAgedFemaleHumansLongitudinal StudiesMaleMiddle AgedPain MeasurementProspective StudiesSex Factors

Identifiers

PMID40780873
PMCPMC12342833

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.