ReviewCanadian journal of surgery. Journal canadien de chirurgie
Canadian considerations on updating the age of initiation for colorectal cancer screening in individuals at average risk.
Review in Canadian journal of surgery. Journal canadien de chirurgie. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Emerging trends in the global burden of colorectal cancer.Nature reviews. Clinical oncology · 2026Review
- Divergent Colorectal Cancer Risks Following Metabolic Bariatric Surgery: Anatomical Remodeling and the Genotoxic Microenvironment.Obesity surgery · 2026Review
- Using Facebook to Improve Participation in Colorectal Cancer Screening: Protocol for a Cluster Randomized Controlled Trial.JMIR research protocols · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The incidence of early-onset colorectal cancer (CRC), defined as CRC occurring in individuals younger than 50 years, is increasing globally. Emerging evidence suggests that the incidence and prevalence of CRC in individuals aged 45-49 years approach those in individuals aged 50-59 years. To address this concerning trend, many health care systems and clinical specialist societies are advocating for lowering the age of initiation for CRC screening in individuals at average risk to 45 years. The present review, provided by the Canadian Association of General Surgeons Clinical Practice Committee, gives an overview of the current CRC screening guidelines in Canada, the rationale for earlier screening, and the challenges and impact of lowering the screening age to 45 years to health care systems in Canada.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.