SynthesisColorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland2025
PAVFCOS: The development of a core outcome set for pouch anal and vaginal fistula.
Synthesis in Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed, 1 synthesis or guideline pooled it.
- PAVFCOS: The development of a core outcome set for pouch anal and vaginal fistula.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2025Pooled it
- Capturing quality of life in pouch anal and vaginal fistula: development of PAVF-QoL-14, a patient-reported outcome measure.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026Article
Corrections and comments
- Erratum issued
Authors and funding
17 authors.
Funding
Abstract
aimsThe primary aim was to develop a patient-centred core outcome set (COS) for interventional studies in patients with pouch anal and vaginal fistula (PAVF).
methodPAVFCOS was developed using the methodology outlined by the Core Outcome Measures in Effectiveness Trials (COMET). Systematic review and qualitative patient interviews produced a long list of candidate outcomes. An online Delphi exercise was conducted with stakeholders to prioritise and shortlist outcomes. A consensus meeting of patients and clinicians ratified the final core outcome set.
resultsA systematic review of the literature and 14 qualitative patient interviews produced a long list of 99 outcomes. These were reduced to 46 outcomes and subjected to two rounds of a Delphi exercise with 70 participants, including patients (45%), colorectal surgeons (31%), radiologists (6%), gastroenterologists (11%) and pouch specialist nurses (7%). Thirty-six outcomes were discussed in a consensus meeting of seven clinicians and seven patients. Seven core outcomes were selected for inclusion: global assessment of continence, pain related to fistula and surrounding area, impact on quality of life of fistula discharge, fistula healing (clinical and radiological), new fistula or abscess, need for rescue intervention (minor or major) and global quality-of-life assessment.
conclusionPAVFCOS is the first to establish outcomes that are important to patients with pouch anal and vaginal fistula. PAVFCOS should be used in interventional studies to introduce much-needed standardisation of outcome reporting in this challenging condition.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.