Evidence map›Paper›PMID 40780813›Full record

ArticleBiopreservation and biobanking2025

Advancing HIV and Cancer Research: Implementing an AIDS and Cancer Specimen Resource in Latin America.

Larissa L S Scholte, Evandro S Mello, Karim Yaqub Ibrahim, Miyuki Uno, Vanesse Maria da Costa, Ellen Sayuri Miazima, Camila Motta Venchiarutti Moniz, Giullia Dias de Souza, Larissa Oliveira Amorim, Isabela Cristina de Souza and 8 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biopreservation and biobanking, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Larissa L S ScholteDepartment of Microbiology, Immunology and Tropical Medicine, The George Washington University, Washington, District of Columbia, USA.ORCID 0000-0001-5671-9960
Evandro S MelloFaculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil.
Karim Yaqub IbrahimCenter for Translational Research in Oncology, Instituto do Câncer do Estado de São Paulo, Hospital das Clinicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil.
Miyuki UnoCenter for Translational Research in Oncology, Instituto do Câncer do Estado de São Paulo, Hospital das Clinicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil.
Vanesse Maria da CostaCenter for Translational Research in Oncology, Instituto do Câncer do Estado de São Paulo, Hospital das Clinicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil.
Ellen Sayuri MiazimaCenter for Translational Research in Oncology, Instituto do Câncer do Estado de São Paulo, Hospital das Clinicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil.
Camila Motta Venchiarutti MonizCenter for Translational Research in Oncology, Instituto do Câncer do Estado de São Paulo, Hospital das Clinicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil.
Giullia Dias de SouzaCenter for Translational Research in Oncology, Instituto do Câncer do Estado de São Paulo, Hospital das Clinicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil.
Larissa Oliveira AmorimCenter for Translational Research in Oncology, Instituto do Câncer do Estado de São Paulo, Hospital das Clinicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil.
Isabela Cristina de SouzaCenter for Translational Research in Oncology, Instituto do Câncer do Estado de São Paulo, Hospital das Clinicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil.
Kris OliveiraCenter for Translational Research in Oncology, Instituto do Câncer do Estado de São Paulo, Hospital das Clinicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil.
Roger ChammasCenter for Translational Research in Oncology, Instituto do Câncer do Estado de São Paulo, Hospital das Clinicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil.
Kristina BowlesCenter for Immunization and Infection Research in Cancer, Cancer Epidemiology Program, Moffitt Cancer Center, Tampa, Florida, USA.
Lipsa DasDepartment of Pathology, University of Arizona, Tucson, Arizona, USA.
Anna E CoghillCenter for Immunization and Infection Research in Cancer, Cancer Epidemiology Program, Moffitt Cancer Center, Tampa, Florida, USA.
Lisa RimszaDepartment of Pathology, University of Arizona, Tucson, Arizona, USA.
Aluisio SeguradoFaculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil.
Jeffrey M BethonyDepartment of Microbiology, Immunology and Tropical Medicine, The George Washington University, Washington, District of Columbia, USA.

Funding

Consortium for Advancing Management and Prevention of Cancer in People with HIVUM1CA121947 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Joseph A. Sparano · 2015 to 2026
$253.7M
AIDS and Cancer Specimen Resource (ACSR)UM1CA181255 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Jeffrey Michael Bethony, Anna Coghill · 2013 to 2026
$56.7M
NCI NIH HHS UM1 CA121947NCI NIH HHS UM1 CA181255
6 · The paper itself

Abstract

The AIDS and Cancer Specimen Resource (ACSR) has developed a global biorepository network to support research on AIDS-defining and non-AIDS-defining cancers. This article details the establishment of a dedicated HIV-associated cancer biorepository in São Paulo, Brazil, a region with a high burden of these malignancies. The repository addresses the need for high-quality, well-annotated biospecimens from Latin American (LATAM) populations to support research on cancer pathogenesis in people with HIV (PWH), viral reservoirs, and clinical outcomes. It systematically collects and links biospecimens with demographic and clinical data, providing a resource for investigators. Developed with international ethics, community engagement, and regulatory standards, the biorepository is modeled after similar efforts in low- and middle-income countries. This article outlines its implementation, including sample acquisition, infrastructure, inventory management, data governance, and research collaboration. By expanding access to biospecimens, the ACSR supports research that can improve outcomes for PWH and cancer, while strengthening research capacity in the LATAM region.

Indexed as

Acquired Immunodeficiency SyndromeBiological Specimen BanksBiomedical ResearchHIV InfectionsNeoplasmsBrazilHumansLatin AmericaSpecimen HandlingbiorepositorycancerHIVtranslational research

Identifiers

PMID40780813
PMCPMC13592566

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.