ArticleJACC. Case reports2025
Delayed Mitral Prosthesis Dehiscence Following Transcatheter Aortic Valve Replacement.
Article in JACC. Case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
6 authors.
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Abstract
backgroundThe presence of preexisting mitral prosthesis in transcatheter aortic valve replacement (TAVR) raises concerns about potential valve interaction; however, this issue remains insufficiently explored. CASE SUMMARY: A 79-year-old man presented with hemolysis 8 months post-TAVR. He had a history of mitral valve replacement 16 years prior. Further investigation revealed severe paravalvular leakage of the mitral valve, which was attributed to the dehiscence of the mitral prosthesis. A retrospective review of pre-TAVR computed tomography images identified a subtle, previously undetected defect in the mitral-aortic intervalvular fibrosa, likely masked by neointima. DISCUSSION: We hypothesize that chronic mechanical stress between the TAVR device and the mitral-aortic intervalvular fibrosa causes progressive damage, resulting in delayed mitral valve dehiscence and hemolysis. TAKE-HOME MESSAGE: Careful preprocedural evaluation and prolonged postprocedural surveillance are essential for patients with preexisting mitral prostheses after TAVR due to the potential for delayed long-term complications.
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