ArticleJACC. Case reports2025
Unilateral Absence of Pulmonary Artery Complicated With Severe Pulmonary Hypertension: Favorable Response to Parenteral Therapy.
Article in JACC. Case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Abstract
backgroundUnilateral absence of pulmonary artery (UAPA) is a rare disorder that can present as an isolated lesion or in association with other congenital heart defects. An important complication of UAPA is the development of pulmonary hypertension (PH). CASE SUMMARY: We discuss an adult patient with severe PH in the setting of congenital UAPA and highlight the hemodynamic response to combination therapy that included parenteral treprostinil. DISCUSSION: To our knowledge, this is the first case report using parenteral treprostinil as part of triple combination therapy to treat PH in setting of UAPA. TAKE-HOME MESSAGES: There are various treatment modalities for severe PH complicating isolated UAPA. This case highlights an additional option, parenteral treprostinil, for physicians to consider in highly selected cases.
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