Evidence map›Paper›PMID 40780776›Full record

ArticleJACC. Case reports2025

Simultaneous Cardiac Surgery for Infective Endocarditis and Liver Transplantation in End-Stage Liver Disease.

Erasmus Mutabi, Ben Boyarko, Emerson Rowe, Aamer Ubaid, Michael Popeck, Tadahiro Uemura, Lorenzo Machado, Thomas Murickan, Masaki Tsukashita

Abstract readCase Reports
In one paragraph

Article in JACC. Case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Erasmus MutabiDepartment of Medicine, Allegheny General Hospital, Pittsburgh, Pennsylvania, USA. Electronic address: emutabi@gmail.com.
Ben BoyarkoDepartment of Medicine, Allegheny General Hospital, Pittsburgh, Pennsylvania, USA.
Emerson RoweDepartment of Medicine, Allegheny General Hospital, Pittsburgh, Pennsylvania, USA.
Aamer UbaidDepartment of Cardiovascular Medicine, Allegheny General Hospital, Pittsburgh, Pennsylvania, USA.
Michael PopeckDepartment of Cardiovascular Medicine, Allegheny General Hospital, Pittsburgh, Pennsylvania, USA.
Tadahiro UemuraDepartment of Transplant and Hepatobiliary Surgery, Allegheny General Hospital, Pittsburgh, Pennsylvania, USA.
Lorenzo MachadoDepartment of Transplant and Hepatobiliary Surgery, Allegheny General Hospital, Pittsburgh, Pennsylvania, USA.
Thomas MurickanDepartment of Transplant and Hepatobiliary Surgery, Allegheny General Hospital, Pittsburgh, Pennsylvania, USA.
Masaki TsukashitaDepartment of Cardiovascular Medicine, Allegheny General Hospital, Pittsburgh, Pennsylvania, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundConcurrent infective endocarditis (IE) and end-stage liver disease present significant perioperative challenges due to overlapping clinical risks. CASE SUMMARY: A 53-year-old man presented with decompensated cirrhosis and IE characterized by severe aortic regurgitation and vegetation extending into the aortomitral curtain. He underwent a complex, yet successful, simultaneous orthotopic liver transplantation and cardiac surgery, which included double valve replacement and reconstruction of the aortomitral curtain using a patch repair. DISCUSSION: Simultaneous cardiac and liver surgery is rarely performed because of overlapping risks of morbidity. This case illustrates the feasibility and potential benefit of a multidisciplinary, single-stage approach in select high-risk patients. TAKE-HOME MESSAGE: Concurrent orthotopic liver transplant surgery and double valve replacement with aorticmitral curtain patch reconstruction for IE can be feasible in very select cases, with successful outcomes hinging on close multidisciplinary collaborations.

Indexed as

acute heart failureendocarditisvalve replacement

Identifiers

PMID40780776
PMCPMC12426547

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.