Evidence map›Paper›PMID 40780767›Full record

ArticleJACC. Case reports2025

Mediastinal Lipoma: An Unusual Cause of Progressive Dyspnea.

Misha A Khan, Yash B Patel, Karldon I Nwaezeapu, Mohammed H El Nayir, Robert C Lyons, Tauqir Y Goraya

Abstract readCase Reports
In one paragraph

Article in JACC. Case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Misha A KhanDepartment of Internal Medicine, Trinity Health Ann Arbor, Ann Arbor, Michigan, USA. Electronic address: Misha.Khan@trinity-health.org.
Yash B PatelDepartment of Internal Medicine, Trinity Health Ann Arbor, Ann Arbor, Michigan, USA.
Karldon I NwaezeapuDepartment of Internal Medicine, Trinity Health Ann Arbor, Ann Arbor, Michigan, USA.
Mohammed H El NayirDepartment of Internal Medicine, Trinity Health Ann Arbor, Ann Arbor, Michigan, USA.
Robert C LyonsSection of Cardiothoracic Surgery, Department of Surgery, Trinity Health Ann Arbor, Ann Arbor, Michigan, USA.
Tauqir Y GorayaSection of Cardiology, Department of Internal Medicine, Trinity Health Michigan Heart Ann Arbor, Ann Arbor, Michigan, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMediastinal lipomas, while rare, can present with progressive dyspnea. CASE SUMMARY: Our case describes a 62-year-old woman presenting with slowly progressive exertional dyspnea over the course of 2 years with a largely unremarkable initial cardiac and pulmonary evaluation. Advanced imaging ultimately revealed a large mediastinal lipoma causing a compressive effect on her left atrium and pulmonary veins. DISCUSSION: This case highlights the importance of considering structural lesions within the mediastinum in the differential diagnosis of exertional dyspnea, particularly when conventional cardiac and pulmonary evaluations fail to elucidate the underlying etiology. TAKE-HOME MESSAGES: Structural lesions, such as slow-growing mediastinal tumors, can cause long-standing progressive exertional dyspnea through mechanical compression of vital structures in the thoracic cavity. Once symptomatic, surgical resection results in symptomatic relief and is curative.

Indexed as

mediastinal lipomasurgical resection

Identifiers

PMID40780767
PMCPMC12426556

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.