ArticleEmerging microbes & infections2025
Two-threshold defined immune non-responders are associated with long-term morbidity in people with HIV: a prospective cohort study.
Article in Emerging microbes & infections, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed.
- Elevated Plasma GDF-15 Levels are Associated with the Immune Non-Responder Phenotype in People with HIV.Infectious diseases and therapy · 2026Article
- Persistent CD8+ T-cell activation (HLA-DR/CD38) as an immunological marker in antiretroviral-treated human immunodeficiency virus-1 patients: A cross-sectional study.The Journal of international medical research · 2026Article
- Article
- Delayed ART initiation and poor immune reconstitution among drug-using HIV patients in two hospitals in China: a retrospective cohort study.BMC infectious diseases · 2026Article
- Dual T-cell exhaustion and hyperactivation profiles identify patients with advanced HIV at high risk for fungal co-infections.BMC infectious diseases · 2026Article
- Metabolic dysbiosis as a predictor of immunological non-response among people living with HIV.Frontiers in cellular and infection microbiology · 2026Article
- Targeting the pDC/IFN-I axis in HIV-1 immunotherapy.Current opinion in HIV and AIDS · 2026Review
- Negative influence of age and low baseline CD4 on T helper cell recovery among HIV-infected individuals with fixed-dose combination of tenofovir disoproxil, lamivudine and dolutegravir.Frontiers in public health · 2026Article
- Tripterygium wilfordii Hook F accelerates CD4Frontiers in pharmacology · 2026Article
- Challenges in the Vaccination of HIV-Infected Individuals.Vaccines · 2025Review
Corrections and comments
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Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A substantial proportion of people with HIV (PWH) fail to achieve full immune recovery despite long-term antiretroviral therapy (ART), potentially increasing their risk of serious comorbidities. This study investigated the association between immune non-responder (INR) and the incidence of AIDS-defining diseases (ADs) and non-AIDS-defining diseases (NADs) in a prospective cohort at the Third People's Hospital of Shenzhen, China. The low - and high-threshold cohorts included 7,874 and 8,077 individuals with baseline CD4
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